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Page 1
Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1.
Lai YC, Kondapalli C, Lehneck R, Procter JB, Dill BD, Woodroof HI, Gourlay R, Peggie M, Macartney TJ, Corti O, Corvol JC, Campbell DG, Itzen A, Trost M, Muqit MM. Lai YC, et al. Among authors: trost m. EMBO J. 2015 Nov 12;34(22):2840-61. doi: 10.15252/embj.201591593. Epub 2015 Oct 15. EMBO J. 2015. PMID: 26471730 Free PMC article.
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.
Kazlauskaite A, Kondapalli C, Gourlay R, Campbell DG, Ritorto MS, Hofmann K, Alessi DR, Knebel A, Trost M, Muqit MM. Kazlauskaite A, et al. Among authors: trost m. Biochem J. 2014 May 15;460(1):127-39. doi: 10.1042/BJ20140334. Biochem J. 2014. PMID: 24660806 Free PMC article.
Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.
Kazlauskaite A, Martínez-Torres RJ, Wilkie S, Kumar A, Peltier J, Gonzalez A, Johnson C, Zhang J, Hope AG, Peggie M, Trost M, van Aalten DM, Alessi DR, Prescott AR, Knebel A, Walden H, Muqit MM. Kazlauskaite A, et al. Among authors: trost m. EMBO Rep. 2015 Aug;16(8):939-54. doi: 10.15252/embr.201540352. Epub 2015 Jun 25. EMBO Rep. 2015. PMID: 26116755 Free PMC article.
A mutant O-GlcNAcase enriches Drosophila developmental regulators.
Selvan N, Williamson R, Mariappa D, Campbell DG, Gourlay R, Ferenbach AT, Aristotelous T, Hopkins-Navratilova I, Trost M, van Aalten DMF. Selvan N, et al. Among authors: trost m. Nat Chem Biol. 2017 Aug;13(8):882-887. doi: 10.1038/nchembio.2404. Epub 2017 Jun 12. Nat Chem Biol. 2017. PMID: 28604694 Free PMC article.
LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages.
Härtlova A, Herbst S, Peltier J, Rodgers A, Bilkei-Gorzo O, Fearns A, Dill BD, Lee H, Flynn R, Cowley SA, Davies P, Lewis PA, Ganley IG, Martinez J, Alessi DR, Reith AD, Trost M, Gutierrez MG. Härtlova A, et al. Among authors: trost m. EMBO J. 2018 Jun 15;37(12):e98694. doi: 10.15252/embj.201798694. Epub 2018 May 22. EMBO J. 2018. PMID: 29789389 Free PMC article.
270 results