Metzner KJ - Search Results

1

Contribution of APOBEC3G/F activity to the development of low-abundance drug-resistant human immunodeficiency virus type 1 variants.

Noguera-Julian M, Cozzi-Lepri A, Di Giallonardo F, Schuurman R, Däumer M, Aitken S, Ceccherini-Silberstein F, D'Arminio Monforte A, Geretti AM, Booth CL, Kaiser R, Michalik C, Jansen K, Masquelier B, Bellecave P, Kouyos RD, Castro E, Furrer H, Schultze A, Günthard HF, Brun-Vezinet F, Metzner KJ, Paredes R; CHAIN Minority HIV-1 Variants Working group. Noguera-Julian M, et al. Among authors: metzner kj. Clin Microbiol Infect. 2016 Feb;22(2):191-200. doi: 10.1016/j.cmi.2015.10.004. Epub 2015 Oct 23. Clin Microbiol Infect. 2016. PMID: 26482266 Free article.

2

Emergence of minor populations of human immunodeficiency virus type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions.

Metzner KJ, Bonhoeffer S, Fischer M, Karanicolas R, Allers K, Joos B, Weber R, Hirschel B, Kostrikis LG, Günthard HF; Swiss HIV Cohort Study. Metzner KJ, et al. J Infect Dis. 2003 Nov 15;188(10):1433-43. doi: 10.1086/379215. Epub 2003 Nov 3. J Infect Dis. 2003. PMID: 14624368

3

Blinded, multicenter comparison of methods to detect a drug-resistant mutant of human immunodeficiency virus type 1 at low frequency.

Halvas EK, Aldrovandi GM, Balfe P, Beck IA, Boltz VF, Coffin JM, Frenkel LM, Hazelwood JD, Johnson VA, Kearney M, Kovacs A, Kuritzkes DR, Metzner KJ, Nissley DV, Nowicki M, Palmer S, Ziermann R, Zhao RY, Jennings CL, Bremer J, Brambilla D, Mellors JW. Halvas EK, et al. Among authors: metzner kj. J Clin Microbiol. 2006 Jul;44(7):2612-4. doi: 10.1128/JCM.00449-06. J Clin Microbiol. 2006. PMID: 16825395 Free PMC article.

4

Persistence of lamivudine-sensitive HIV-1 quasispecies in the presence of lamivudine in vitro and in vivo.

Allers K, Knoepfel SA, Rauch P, Walter H, Opravil M, Fischer M, Günthard HF, Metzner KJ. Allers K, et al. Among authors: metzner kj. J Acquir Immune Defic Syndr. 2007 Apr 1;44(4):377-85. doi: 10.1097/QAI.0b013e31803104c0. J Acquir Immune Defic Syndr. 2007. PMID: 17211280

5

Comparison of G-to-A mutation frequencies induced by APOBEC3 proteins in H9 cells and peripheral blood mononuclear cells in the context of impaired processivities of drug-resistant human immunodeficiency virus type 1 reverse transcriptase variants.

Knoepfel SA, Salisch NC, Huelsmann PM, Rauch P, Walter H, Metzner KJ. Knoepfel SA, et al. Among authors: metzner kj. J Virol. 2008 Jul;82(13):6536-45. doi: 10.1128/JVI.00554-08. Epub 2008 Apr 30. J Virol. 2008. PMID: 18448538 Free PMC article.

6

Minority quasispecies of drug-resistant HIV-1 that lead to early therapy failure in treatment-naive and -adherent patients.

Metzner KJ, Giulieri SG, Knoepfel SA, Rauch P, Burgisser P, Yerly S, Günthard HF, Cavassini M. Metzner KJ, et al. Clin Infect Dis. 2009 Jan 15;48(2):239-47. doi: 10.1086/595703. Clin Infect Dis. 2009. PMID: 19086910 Free article.

7

Rational design of HIV-1 fluorescent hydrolysis probes considering phylogenetic variation and probe performance.

Althaus CF, Gianella S, Rieder P, von Wyl V, Kouyos RD, Niederöst B, Schmid A, Metzner KJ, Joos B, Günthard HF, Fischer M. Althaus CF, et al. Among authors: metzner kj. J Virol Methods. 2010 May;165(2):151-60. doi: 10.1016/j.jviromet.2010.01.012. Epub 2010 Jan 29. J Virol Methods. 2010. PMID: 20116399 Free article.

8

Efficient suppression of minority drug-resistant HIV type 1 (HIV-1) variants present at primary HIV-1 infection by ritonavir-boosted protease inhibitor-containing antiretroviral therapy.

Metzner KJ, Rauch P, von Wyl V, Leemann C, Grube C, Kuster H, Böni J, Weber R, Günthard HF. Metzner KJ, et al. J Infect Dis. 2010 Apr 1;201(7):1063-71. doi: 10.1086/651136. J Infect Dis. 2010. PMID: 20196655 Free article.

9

Profound depletion of HIV-1 transcription in patients initiating antiretroviral therapy during acute infection.

Schmid A, Gianella S, von Wyl V, Metzner KJ, Scherrer AU, Niederöst B, Althaus CF, Rieder P, Grube C, Joos B, Weber R, Fischer M, Günthard HF. Schmid A, et al. Among authors: metzner kj. PLoS One. 2010 Oct 12;5(10):e13310. doi: 10.1371/journal.pone.0013310. PLoS One. 2010. PMID: 20967271 Free PMC article.

10

Prevalence of key resistance mutations K65R, K103N, and M184V as minority HIV-1 variants in chronically HIV-1 infected, treatment-naïve patients.

Metzner KJ, Rauch P, Braun P, Knechten H, Ehret R, Korn K, Kaiser R, Sichtig N, Ranneberg B, van Lunzen J, Walter H. Metzner KJ, et al. J Clin Virol. 2011 Feb;50(2):156-61. doi: 10.1016/j.jcv.2010.10.001. Epub 2010 Nov 4. J Clin Virol. 2011. PMID: 21056001

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