Packham G - Search Results

1

The SF3B1 inhibitor spliceostatin A (SSA) elicits apoptosis in chronic lymphocytic leukaemia cells through downregulation of Mcl-1.

Larrayoz M, Blakemore SJ, Dobson RC, Blunt MD, Rose-Zerilli MJ, Walewska R, Duncombe A, Oscier D, Koide K, Forconi F, Packham G, Yoshida M, Cragg MS, Strefford JC, Steele AJ. Larrayoz M, et al. Among authors: packham g. Leukemia. 2016 Feb;30(2):351-60. doi: 10.1038/leu.2015.286. Epub 2015 Oct 21. Leukemia. 2016. PMID: 26488112

2

Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukemia.

Lanham S, Hamblin T, Oscier D, Ibbotson R, Stevenson F, Packham G. Lanham S, et al. Among authors: packham g. Blood. 2003 Feb 1;101(3):1087-93. doi: 10.1182/blood-2002-06-1822. Epub 2002 Sep 26. Blood. 2003. PMID: 12393552 Free article.

3

Mcl-1.

Michels J, Johnson PW, Packham G. Michels J, et al. Among authors: packham g. Int J Biochem Cell Biol. 2005 Feb;37(2):267-71. doi: 10.1016/j.biocel.2004.04.007. Int J Biochem Cell Biol. 2005. PMID: 15474972 Review.

4

Bodyguards and assassins: Bcl-2 family proteins and apoptosis control in chronic lymphocytic leukaemia.

Packham G, Stevenson FK. Packham G, et al. Immunology. 2005 Apr;114(4):441-9. doi: 10.1111/j.1365-2567.2005.02117.x. Immunology. 2005. PMID: 15804279 Free PMC article. Review.

5

Structural and functional features of the B-cell receptor in IgG-positive chronic lymphocytic leukemia.

Potter KN, Mockridge CI, Neville L, Wheatley I, Schenk M, Orchard J, Duncombe AS, Packham G, Stevenson FK. Potter KN, et al. Among authors: packham g. Clin Cancer Res. 2006 Mar 15;12(6):1672-9. doi: 10.1158/1078-0432.CCR-05-2164. Clin Cancer Res. 2006. PMID: 16551848

6

Pharmacological inhibitors of NF-kappaB accelerate apoptosis in chronic lymphocytic leukaemia cells.

Pickering BM, de Mel S, Lee M, Howell M, Habens F, Dallman CL, Neville LA, Potter KN, Mann J, Mann DA, Johnson PW, Stevenson FK, Packham G. Pickering BM, et al. Among authors: packham g. Oncogene. 2007 Feb 22;26(8):1166-77. doi: 10.1038/sj.onc.1209897. Epub 2006 Aug 21. Oncogene. 2007. PMID: 16924235

7

Induction of cytosolic calcium flux by CD20 is dependent upon B Cell antigen receptor signaling.

Walshe CA, Beers SA, French RR, Chan CH, Johnson PW, Packham GK, Glennie MJ, Cragg MS. Walshe CA, et al. J Biol Chem. 2008 Jun 20;283(25):16971-84. doi: 10.1074/jbc.M708459200. Epub 2008 Apr 21. J Biol Chem. 2008. PMID: 18426802 Free article.

8

Inhibition of proteasomal degradation of Mcl-1 by cobalt chloride suppresses cobalt chloride-induced apoptosis in HCT116 colorectal cancer cells.

Lee M, Lapham A, Brimmell M, Wilkinson H, Packham G. Lee M, et al. Among authors: packham g. Apoptosis. 2008 Aug;13(8):972-82. doi: 10.1007/s10495-008-0229-2. Apoptosis. 2008. PMID: 18543107

9

The role of the B-cell receptor in the pathogenesis of chronic lymphocytic leukaemia.

Packham G, Stevenson F. Packham G, et al. Semin Cancer Biol. 2010 Dec;20(6):391-9. doi: 10.1016/j.semcancer.2010.08.004. Epub 2010 Sep 9. Semin Cancer Biol. 2010. PMID: 20816790 Review.

10

B-cell receptor signaling in chronic lymphocytic leukemia.

Stevenson FK, Krysov S, Davies AJ, Steele AJ, Packham G. Stevenson FK, et al. Among authors: packham g. Blood. 2011 Oct 20;118(16):4313-20. doi: 10.1182/blood-2011-06-338855. Epub 2011 Aug 3. Blood. 2011. PMID: 21816833 Free article.

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