Pruss RM - Search Results

1

Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat.

Clemens LE, Weber JJ, Wlodkowski TT, Yu-Taeger L, Michaud M, Calaminus C, Eckert SH, Gaca J, Weiss A, Magg JC, Jansson EK, Eckert GP, Pichler BJ, Bordet T, Pruss RM, Riess O, Nguyen HP. Clemens LE, et al. Among authors: pruss rm. Brain. 2015 Dec;138(Pt 12):3632-53. doi: 10.1093/brain/awv290. Epub 2015 Oct 21. Brain. 2015. PMID: 26490331

2

Mitochondrial membrane fluidity is consistently increased in different models of Huntington disease: restorative effects of olesoxime.

Eckmann J, Clemens LE, Eckert SH, Hagl S, Yu-Taeger L, Bordet T, Pruss RM, Muller WE, Leuner K, Nguyen HP, Eckert GP. Eckmann J, et al. Among authors: pruss rm. Mol Neurobiol. 2014 Aug;50(1):107-18. doi: 10.1007/s12035-014-8663-3. Epub 2014 Mar 18. Mol Neurobiol. 2014. PMID: 24633813

3

Olesoxime delays muscle denervation, astrogliosis, microglial activation and motoneuron death in an ALS mouse model.

Sunyach C, Michaud M, Arnoux T, Bernard-Marissal N, Aebischer J, Latyszenok V, Gouarné C, Raoul C, Pruss RM, Bordet T, Pettmann B. Sunyach C, et al. Among authors: pruss rm. Neuropharmacology. 2012 Jun;62(7):2346-52. doi: 10.1016/j.neuropharm.2012.02.013. Epub 2012 Feb 20. Neuropharmacology. 2012. PMID: 22369784

4

Early deficits in glycolysis are specific to striatal neurons from a rat model of huntington disease.

Gouarné C, Tardif G, Tracz J, Latyszenok V, Michaud M, Clemens LE, Yu-Taeger L, Nguyen HP, Bordet T, Pruss RM. Gouarné C, et al. Among authors: pruss rm. PLoS One. 2013 Nov 26;8(11):e81528. doi: 10.1371/journal.pone.0081528. eCollection 2013. PLoS One. 2013. PMID: 24303051 Free PMC article.

5

Targeting neuroprotection as an alternative approach to preventing and treating neuropathic pain.

Bordet T, Pruss RM. Bordet T, et al. Among authors: pruss rm. Neurotherapeutics. 2009 Oct;6(4):648-62. doi: 10.1016/j.nurt.2009.07.001. Neurotherapeutics. 2009. PMID: 19789070 Free PMC article. Review.

6

Olesoxime accelerates myelination and promotes repair in models of demyelination.

Magalon K, Zimmer C, Cayre M, Khaldi J, Bourbon C, Robles I, Tardif G, Viola A, Pruss RM, Bordet T, Durbec P. Magalon K, et al. Among authors: pruss rm. Ann Neurol. 2012 Feb;71(2):213-26. doi: 10.1002/ana.22593. Ann Neurol. 2012. PMID: 22367994

7

Olesoxime protects embryonic cortical neurons from camptothecin intoxication by a mechanism distinct from BDNF.

Gouarné C, Giraudon-Paoli M, Seimandi M, Biscarrat C, Tardif G, Pruss RM, Bordet T. Gouarné C, et al. Among authors: pruss rm. Br J Pharmacol. 2013 Apr;168(8):1975-88. doi: 10.1111/bph.12094. Br J Pharmacol. 2013. PMID: 23278424 Free PMC article.

8

Olesoxime (TRO19622): A Novel Mitochondrial-Targeted Neuroprotective Compound.

Bordet T, Berna P, Abitbol JL, Pruss RM. Bordet T, et al. Among authors: pruss rm. Pharmaceuticals (Basel). 2010 Jan 28;3(2):345-368. doi: 10.3390/ph3020345. Pharmaceuticals (Basel). 2010. PMID: 27713255 Free PMC article. Review.

9

Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis.

Bordet T, Buisson B, Michaud M, Drouot C, Galéa P, Delaage P, Akentieva NP, Evers AS, Covey DF, Ostuni MA, Lacapère JJ, Massaad C, Schumacher M, Steidl EM, Maux D, Delaage M, Henderson CE, Pruss RM. Bordet T, et al. Among authors: pruss rm. J Pharmacol Exp Ther. 2007 Aug;322(2):709-20. doi: 10.1124/jpet.107.123000. Epub 2007 May 11. J Pharmacol Exp Ther. 2007. PMID: 17496168

10

Specific antinociceptive activity of cholest-4-en-3-one, oxime (TRO19622) in experimental models of painful diabetic and chemotherapy-induced neuropathy.

Bordet T, Buisson B, Michaud M, Abitbol JL, Marchand F, Grist J, Andriambeloson E, Malcangio M, Pruss RM. Bordet T, et al. Among authors: pruss rm. J Pharmacol Exp Ther. 2008 Aug;326(2):623-32. doi: 10.1124/jpet.108.139410. Epub 2008 May 20. J Pharmacol Exp Ther. 2008. PMID: 18492948

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