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Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes.
Sanborn AL, Rao SS, Huang SC, Durand NC, Huntley MH, Jewett AI, Bochkov ID, Chinnappan D, Cutkosky A, Li J, Geeting KP, Gnirke A, Melnikov A, McKenna D, Stamenova EK, Lander ES, Aiden EL. Sanborn AL, et al. Among authors: chinnappan d. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6456-65. doi: 10.1073/pnas.1518552112. Epub 2015 Oct 23. Proc Natl Acad Sci U S A. 2015. PMID: 26499245 Free PMC article.
Deregulated Aurora-B induced tetraploidy promotes tumorigenesis.
Nguyen HG, Makitalo M, Yang D, Chinnappan D, St Hilaire C, Ravid K. Nguyen HG, et al. Among authors: chinnappan d. FASEB J. 2009 Aug;23(8):2741-8. doi: 10.1096/fj.09-130963. Epub 2009 Mar 30. FASEB J. 2009. PMID: 19332642 Free PMC article.
22 results