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Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes.
Sanborn AL, Rao SS, Huang SC, Durand NC, Huntley MH, Jewett AI, Bochkov ID, Chinnappan D, Cutkosky A, Li J, Geeting KP, Gnirke A, Melnikov A, McKenna D, Stamenova EK, Lander ES, Aiden EL. Sanborn AL, et al. Among authors: gnirke a. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6456-65. doi: 10.1073/pnas.1518552112. Epub 2015 Oct 23. Proc Natl Acad Sci U S A. 2015. PMID: 26499245 Free PMC article.
High-quality draft assemblies of mammalian genomes from massively parallel sequence data.
Gnerre S, Maccallum I, Przybylski D, Ribeiro FJ, Burton JN, Walker BJ, Sharpe T, Hall G, Shea TP, Sykes S, Berlin AM, Aird D, Costello M, Daza R, Williams L, Nicol R, Gnirke A, Nusbaum C, Lander ES, Jaffe DB. Gnerre S, et al. Among authors: gnirke a. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1513-8. doi: 10.1073/pnas.1017351108. Epub 2010 Dec 27. Proc Natl Acad Sci U S A. 2011. PMID: 21187386 Free PMC article.
Comprehensive mapping of long-range interactions reveals folding principles of the human genome.
Lieberman-Aiden E, van Berkum NL, Williams L, Imakaev M, Ragoczy T, Telling A, Amit I, Lajoie BR, Sabo PJ, Dorschner MO, Sandstrom R, Bernstein B, Bender MA, Groudine M, Gnirke A, Stamatoyannopoulos J, Mirny LA, Lander ES, Dekker J. Lieberman-Aiden E, et al. Among authors: gnirke a. Science. 2009 Oct 9;326(5950):289-93. doi: 10.1126/science.1181369. Science. 2009. PMID: 19815776 Free PMC article.
Targeted bisulfite sequencing of the dynamic DNA methylome.
Ziller MJ, Stamenova EK, Gu H, Gnirke A, Meissner A. Ziller MJ, et al. Among authors: gnirke a. Epigenetics Chromatin. 2016 Dec 3;9:55. doi: 10.1186/s13072-016-0105-1. eCollection 2016. Epigenetics Chromatin. 2016. PMID: 27980681 Free PMC article.
Hi-C: a method to study the three-dimensional architecture of genomes.
van Berkum NL, Lieberman-Aiden E, Williams L, Imakaev M, Gnirke A, Mirny LA, Dekker J, Lander ES. van Berkum NL, et al. Among authors: gnirke a. J Vis Exp. 2010 May 6;(39):1869. doi: 10.3791/1869. J Vis Exp. 2010. PMID: 20461051 Free PMC article.
124 results