Huibregtse JM - Search Results

1

Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners.

O'Connor HF, Lyon N, Leung JW, Agarwal P, Swaim CD, Miller KM, Huibregtse JM. O'Connor HF, et al. Among authors: huibregtse jm. EMBO Rep. 2015 Dec;16(12):1699-712. doi: 10.15252/embr.201540620. Epub 2015 Oct 27. EMBO Rep. 2015. PMID: 26508657 Free PMC article.

2

Enzyme-substrate relationships in the ubiquitin system: approaches for identifying substrates of ubiquitin ligases.

O'Connor HF, Huibregtse JM. O'Connor HF, et al. Among authors: huibregtse jm. Cell Mol Life Sci. 2017 Sep;74(18):3363-3375. doi: 10.1007/s00018-017-2529-6. Epub 2017 Apr 28. Cell Mol Life Sci. 2017. PMID: 28455558 Free PMC article. Review.

3

Ubiquitin-Activated Interaction Traps (UBAITs): Tools for Capturing Protein-Protein Interactions.

O'Connor HF, Swaim CD, Canadeo LA, Huibregtse JM. O'Connor HF, et al. Among authors: huibregtse jm. Methods Mol Biol. 2018;1844:85-100. doi: 10.1007/978-1-4939-8706-1_7. Methods Mol Biol. 2018. PMID: 30242705

4

The Rsp5 ubiquitin ligase is coupled to and antagonized by the Ubp2 deubiquitinating enzyme.

Kee Y, Lyon N, Huibregtse JM. Kee Y, et al. Among authors: huibregtse jm. EMBO J. 2005 Jul 6;24(13):2414-24. doi: 10.1038/sj.emboj.7600710. Epub 2005 Jun 2. EMBO J. 2005. PMID: 15933713 Free PMC article.

5

The deubiquitinating enzyme Ubp2 modulates Rsp5-dependent Lys63-linked polyubiquitin conjugates in Saccharomyces cerevisiae.

Kee Y, Muñoz W, Lyon N, Huibregtse JM. Kee Y, et al. Among authors: huibregtse jm. J Biol Chem. 2006 Dec 1;281(48):36724-31. doi: 10.1074/jbc.M608756200. Epub 2006 Oct 6. J Biol Chem. 2006. PMID: 17028178 Free article.

6

Structure and function of a HECT domain ubiquitin-binding site.

Kim HC, Steffen AM, Oldham ML, Chen J, Huibregtse JM. Kim HC, et al. Among authors: huibregtse jm. EMBO Rep. 2011 Apr;12(4):334-41. doi: 10.1038/embor.2011.23. Epub 2011 Mar 11. EMBO Rep. 2011. PMID: 21399621 Free PMC article.

7

The -4 phenylalanine is required for substrate ubiquitination catalyzed by HECT ubiquitin ligases.

Salvat C, Wang G, Dastur A, Lyon N, Huibregtse JM. Salvat C, et al. Among authors: huibregtse jm. J Biol Chem. 2004 Apr 30;279(18):18935-43. doi: 10.1074/jbc.M312201200. Epub 2004 Feb 13. J Biol Chem. 2004. PMID: 14966115 Free article.

8

A single PXY motif located within the carboxyl terminus of Spt23p and Mga2p mediates a physical and functional interaction with ubiquitin ligase Rsp5p.

Shcherbik N, Kee Y, Lyon N, Huibregtse JM, Haines DS. Shcherbik N, et al. Among authors: huibregtse jm. J Biol Chem. 2004 Dec 17;279(51):53892-8. doi: 10.1074/jbc.M410325200. Epub 2004 Oct 5. J Biol Chem. 2004. PMID: 15466864 Free article.

9

The ISG15 conjugation system broadly targets newly synthesized proteins: implications for the antiviral function of ISG15.

Durfee LA, Lyon N, Seo K, Huibregtse JM. Durfee LA, et al. Among authors: huibregtse jm. Mol Cell. 2010 Jun 11;38(5):722-32. doi: 10.1016/j.molcel.2010.05.002. Mol Cell. 2010. PMID: 20542004 Free PMC article.

10

Extracellular ISG15 Signals Cytokine Secretion through the LFA-1 Integrin Receptor.

Swaim CD, Scott AF, Canadeo LA, Huibregtse JM. Swaim CD, et al. Among authors: huibregtse jm. Mol Cell. 2017 Nov 2;68(3):581-590.e5. doi: 10.1016/j.molcel.2017.10.003. Mol Cell. 2017. PMID: 29100055 Free PMC article.

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