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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.
Prentice LM, Miller RR, Knaggs J, Mazloomian A, Aguirre Hernandez R, Franchini P, Parsa K, Tessier-Cloutier B, Lapuk A, Huntsman D, Schaeffer DF, Sheffield BS. Prentice LM, et al. Among authors: mazloomian a. PLoS One. 2018 Apr 26;13(4):e0196434. doi: 10.1371/journal.pone.0196434. eCollection 2018. PLoS One. 2018. PMID: 29698444 Free PMC article.