Dickmann LJ - Search Results

1

Evaluation of Fluorophotometry to Assess the Vitreal Pharmacokinetics of Protein Therapeutics.

Dickmann LJ, Yip V, Li C, Abundes J Jr, Maia M, Young C, Stainton S, Hass PE, Joseph SB, Prabhu S, Boswell CA. Dickmann LJ, et al. Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6991-9. doi: 10.1167/iovs.15-17457. Invest Ophthalmol Vis Sci. 2015. PMID: 26513505

2

Contribution of Antibody Hydrodynamic Size to Vitreal Clearance Revealed through Rabbit Studies Using a Species-Matched Fab.

Shatz W, Hass PE, Mathieu M, Kim HS, Leach K, Zhou M, Crawford Y, Shen A, Wang K, Chang DP, Maia M, Crowell SR, Dickmann L, Scheer JM, Kelley RF. Shatz W, et al. Mol Pharm. 2016 Sep 6;13(9):2996-3003. doi: 10.1021/acs.molpharmaceut.6b00345. Epub 2016 Jun 14. Mol Pharm. 2016. PMID: 27244474

3

Pharmacokinetics, metabolism and distribution of PEGs and PEGylated proteins: quo vadis?

Baumann A, Tuerck D, Prabhu S, Dickmann L, Sims J. Baumann A, et al. Drug Discov Today. 2014 Oct;19(10):1623-31. doi: 10.1016/j.drudis.2014.06.002. Epub 2014 Jun 11. Drug Discov Today. 2014. PMID: 24929223 Review.

4

Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye.

Tesar D, Luoma J, Wyatt EA, Shi C, Shatz W, Hass PE, Mathieu M, Yi L, Corn JE, Maass KF, Wang K, Dion MZ, Andersen N, Loyet KM, van Lookeren Campagne M, Rajagopal K, Dickmann L, Scheer JM, Kelley RF. Tesar D, et al. MAbs. 2017 Nov/Dec;9(8):1297-1305. doi: 10.1080/19420862.2017.1372078. Epub 2017 Aug 30. MAbs. 2017. PMID: 28854082 Free PMC article.

5

In Vivo Stability Profiles of Anti-factor D Molecules Support Long-Acting Delivery Approaches.

Loyet KM, Hass PE, Sandoval WN, Morando A, Liu P, Shatz W, Dickmann L, Kenrick M, Good J, Davancaze T, Morimoto AM, Kelley RF, Scheer JM. Loyet KM, et al. Mol Pharm. 2019 Jan 7;16(1):86-95. doi: 10.1021/acs.molpharmaceut.8b00871. Epub 2018 Dec 3. Mol Pharm. 2019. PMID: 30444371

6

Ocular Therapeutics: Drug Delivery and Pharmacology.

Dickmann L. Dickmann L. Mol Pharm. 2016 Sep 6;13(9):2875-6. doi: 10.1021/acs.molpharmaceut.6b00703. Mol Pharm. 2016. PMID: 27596048 No abstract available.

7

Intrinsic and Extrinsic Pharmacokinetic Variability of Small Molecule Targeted Cancer Therapy.

Reyner E, Lum B, Jing J, Kagedal M, Ware JA, Dickmann LJ. Reyner E, et al. Among authors: dickmann lj. Clin Transl Sci. 2020 Mar;13(2):410-418. doi: 10.1111/cts.12726. Epub 2019 Dec 12. Clin Transl Sci. 2020. PMID: 31729137 Free PMC article.

8

Assessment of Disease-Related Therapeutic Protein Drug-Drug Interaction for Etrolizumab in Patients With Moderately to Severely Active Ulcerative Colitis.

Wei X, Kenny JR, Dickmann L, Maciuca R, Looney C, Tang MT. Wei X, et al. J Clin Pharmacol. 2016 Jun;56(6):693-704. doi: 10.1002/jcph.649. Epub 2016 Jan 11. J Clin Pharmacol. 2016. PMID: 26412221 Free PMC article. Clinical Trial.

9

Pharmacogenomics in the age of personalized medicine.

Dickmann LJ, Ware JA. Dickmann LJ, et al. Drug Discov Today Technol. 2016 Sep-Dec;21-22:11-16. doi: 10.1016/j.ddtec.2016.11.003. Drug Discov Today Technol. 2016. PMID: 27978982 Review.

10

Quantitative systems pharmacology model-based investigation of adverse gastrointestinal events associated with prolonged treatment with PI3-kinase inhibitors.

Gadkar K, Friedrich C, Hurez V, Ruiz ML, Dickmann L, Kumar Jolly M, Schutt L, Jin J, Ware JA, Ramanujan S. Gadkar K, et al. CPT Pharmacometrics Syst Pharmacol. 2022 May;11(5):616-627. doi: 10.1002/psp4.12749. Epub 2021 Dec 13. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 34850607 Free PMC article.

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