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Optimization of upcyte® human hepatocytes for the in vitro micronucleus assay.
Nörenberg A, Heinz S, Scheller K, Hewitt NJ, Braspenning J, Ott M. Nörenberg A, et al. Among authors: hewitt nj. Mutat Res Genet Toxicol Environ Mutagen. 2013 Dec 12;758(1-2):69-79. doi: 10.1016/j.mrgentox.2013.09.008. Epub 2013 Oct 16. Mutat Res Genet Toxicol Environ Mutagen. 2013. PMID: 24140631
Cryopreservation of Hepatocytes.
Hewitt NJ, Li AP. Hewitt NJ, et al. Methods Mol Biol. 2015;1250:13-26. doi: 10.1007/978-1-4939-2074-7_2. Methods Mol Biol. 2015. PMID: 26272132
Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.
Hewitt NJ, Lechón MJ, Houston JB, Hallifax D, Brown HS, Maurel P, Kenna JG, Gustavsson L, Lohmann C, Skonberg C, Guillouzo A, Tuschl G, Li AP, LeCluyse E, Groothuis GM, Hengstler JG. Hewitt NJ, et al. Drug Metab Rev. 2007;39(1):159-234. doi: 10.1080/03602530601093489. Drug Metab Rev. 2007. PMID: 17364884 Review.
92 results