Orsatti L - Search Results

1

Use of 'dilute-and-shoot' liquid chromatography-high resolution mass spectrometry in preclinical research: application to a DMPK study of perhexiline in mouse plasma.

Esposito S, Bracacel E, Nibbio M, Speziale R, Orsatti L, Veneziano M, Monteagudo E, Bonelli F. Esposito S, et al. Among authors: orsatti l. J Pharm Biomed Anal. 2016 Jan 25;118:70-80. doi: 10.1016/j.jpba.2015.10.004. Epub 2015 Oct 17. J Pharm Biomed Anal. 2016. PMID: 26517851

2

Characterization of the hepatitis C virus NS2/3 processing reaction by using a purified precursor protein.

Pallaoro M, Lahm A, Biasiol G, Brunetti M, Nardella C, Orsatti L, Bonelli F, Orrù S, Narjes F, Steinkühler C. Pallaoro M, et al. Among authors: orsatti l. J Virol. 2001 Oct;75(20):9939-46. doi: 10.1128/JVI.75.20.9939-9946.2001. J Virol. 2001. PMID: 11559826 Free PMC article.

3

Reactivity of the NS2/3(907-1206)ASK(4) protein with beta-mercaptoethanol studied by electrospray ion trap mass spectrometry.

Orsatti L, Pallaoro M, Steinküler C, Orru' S, Bonelli F. Orsatti L, et al. Rapid Commun Mass Spectrom. 2002;16(20):1919-27. doi: 10.1002/rcm.814. Rapid Commun Mass Spectrom. 2002. PMID: 12362382

4

Determination of the stoichiometry of noncovalent complexes using reverse-phase high-performance liquid chromatography coupled with electrospray ion trap mass spectrometry.

Orsatti L, Di Marco S, Volpari C, Vannini A, Neddermann P, Bonelli F. Orsatti L, et al. Anal Biochem. 2002 Oct 1;309(1):11-8. doi: 10.1016/s0003-2697(02)00295-6. Anal Biochem. 2002. PMID: 12381356

5

A single-run liquid chromatography mass spectrometry method to quantify neuroactive kynurenine pathway metabolites in rat plasma.

Orsatti L, Speziale R, Orsale MV, Caretti F, Veneziano M, Zini M, Monteagudo E, Lyons K, Beconi M, Chan K, Herbst T, Toledo-Sherman L, Munoz-Sanjuan I, Bonelli F, Dominguez C. Orsatti L, et al. J Pharm Biomed Anal. 2015 Mar 25;107:426-31. doi: 10.1016/j.jpba.2015.01.030. Epub 2015 Jan 24. J Pharm Biomed Anal. 2015. PMID: 25668794

6

An efficient liquid chromatography-high resolution mass spectrometry approach for the optimization of the metabolic stability of therapeutic peptides.

Esposito S, Mele R, Ingenito R, Bianchi E, Bonelli F, Monteagudo E, Orsatti L. Esposito S, et al. Among authors: orsatti l. Anal Bioanal Chem. 2017 Apr;409(10):2685-2696. doi: 10.1007/s00216-017-0213-1. Epub 2017 Jan 30. Anal Bioanal Chem. 2017. PMID: 28138743

7

Determination of acetyl coenzyme A in human whole blood by ultra-performance liquid chromatography-mass spectrometry.

Speziale R, Montesano C, De Leonibus ML, Bonelli F, Fezzardi P, Beconi MG, Monteagudo E, Elbaum D, Orsatti L. Speziale R, et al. Among authors: orsatti l. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Apr 15;1083:57-62. doi: 10.1016/j.jchromb.2018.02.039. Epub 2018 Mar 2. J Chromatogr B Analyt Technol Biomed Life Sci. 2018. PMID: 29524693

8

A liquid chromatography high-resolution mass spectrometry in vitro assay to assess metabolism at the injection site of subcutaneously administered therapeutic peptides.

Esposito S, de Leonibus ML, Ingenito R, Bianchi E, Orsatti L, Monteagudo E. Esposito S, et al. Among authors: orsatti l. J Pharm Biomed Anal. 2018 Sep 10;159:449-458. doi: 10.1016/j.jpba.2018.07.009. Epub 2018 Jul 10. J Pharm Biomed Anal. 2018. PMID: 30041153

9

Comparison of different protein precipitation and solid-phase extraction protocols for the study of the catabolism of peptide drugs by LC-HRMS.

Esposito S, Vanni D, Menta S, Orsatti L, Monteagudo E. Esposito S, et al. Among authors: orsatti l. J Pept Sci. 2020 Sep;26(9):e3272. doi: 10.1002/psc.3272. Epub 2020 Jul 6. J Pept Sci. 2020. PMID: 32633064

10

Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand.

Liu L, Prime ME, Lee MR, Khetarpal V, Brown CJ, Johnson PD, Miranda-Azpiazu P, Chen X, Clark-Frew D, Coe S, Davis R, Dickie A, Ebneth A, Esposito S, Gadouleau E, Gai X, Galan S, Green S, Greenaway C, Giles P, Halldin C, Hayes S, Herbst T, Herrmann F, Heßmann M, Jia Z, Kiselyov A, Kotey A, Krulle T, Mangette JE, Marston RW, Menta S, Mills MR, Monteagudo E, Nag S, Nibbio M, Orsatti L, Schaertl S, Scheich C, Sproston J, Stepanov V, Svedberg M, Takano A, Taylor M, Thomas W, Toth M, Vaidya D, Vanräs K, Weddell D, Wigginton I, Wityak J, Mrzljak L, Munoz-Sanjuan I, Bard JA, Dominguez C. Liu L, et al. Among authors: orsatti l. J Med Chem. 2020 Aug 13;63(15):8608-8633. doi: 10.1021/acs.jmedchem.0c00955. Epub 2020 Jul 30. J Med Chem. 2020. PMID: 32662649

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