Mowbray SL - Search Results

1

Expanding the Catalytic Triad in Epoxide Hydrolases and Related Enzymes.

Amrein BA, Bauer P, Duarte F, Janfalk Carlsson Å, Naworyta A, Mowbray SL, Widersten M, Kamerlin SC. Amrein BA, et al. Among authors: mowbray sl. ACS Catal. 2015 Oct 2;5(10):5702-5713. doi: 10.1021/acscatal.5b01639. Epub 2015 Aug 17. ACS Catal. 2015. PMID: 26527505 Free PMC article.

2

X-ray structure of potato epoxide hydrolase sheds light on substrate specificity in plant enzymes.

Mowbray SL, Elfström LT, Ahlgren KM, Andersson CE, Widersten M. Mowbray SL, et al. Protein Sci. 2006 Jul;15(7):1628-37. doi: 10.1110/ps.051792106. Epub 2006 Jun 2. Protein Sci. 2006. PMID: 16751602 Free PMC article.

3

Removal of distal protein-water hydrogen bonds in a plant epoxide hydrolase increases catalytic turnover but decreases thermostability.

Thomaeus A, Naworyta A, Mowbray SL, Widersten M. Thomaeus A, et al. Among authors: mowbray sl. Protein Sci. 2008 Jul;17(7):1275-84. doi: 10.1110/ps.034173.107. Epub 2008 May 30. Protein Sci. 2008. PMID: 18515642 Free PMC article.

4

Directed evolution of an enantioselective epoxide hydrolase: uncovering the source of enantioselectivity at each evolutionary stage.

Reetz MT, Bocola M, Wang LW, Sanchis J, Cronin A, Arand M, Zou J, Archelas A, Bottalla AL, Naworyta A, Mowbray SL. Reetz MT, et al. Among authors: mowbray sl. J Am Chem Soc. 2009 Jun 3;131(21):7334-43. doi: 10.1021/ja809673d. J Am Chem Soc. 2009. PMID: 19469578 Free article.

5

Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family.

Stern AL, Naworyta A, Cazzulo JJ, Mowbray SL. Stern AL, et al. Among authors: mowbray sl. FEBS J. 2011 Mar;278(5):793-808. doi: 10.1111/j.1742-4658.2010.07999.x. Epub 2011 Jan 25. FEBS J. 2011. PMID: 21205211 Free article.

6

Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents.

Russo F, Gising J, Åkerbladh L, Roos AK, Naworyta A, Mowbray SL, Sokolowski A, Henderson I, Alling T, Bailey MA, Files M, Parish T, Karlén A, Larhed M. Russo F, et al. Among authors: mowbray sl. ChemistryOpen. 2015 Jun;4(3):342-62. doi: 10.1002/open.201500001. Epub 2015 Apr 17. ChemistryOpen. 2015. PMID: 26246997 Free PMC article.

7

Structure of Aspergillus niger epoxide hydrolase at 1.8 A resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases.

Zou J, Hallberg BM, Bergfors T, Oesch F, Arand M, Mowbray SL, Jones TA. Zou J, et al. Among authors: mowbray sl. Structure. 2000 Feb 15;8(2):111-22. doi: 10.1016/s0969-2126(00)00087-3. Structure. 2000. PMID: 10673439 Free article.

8

Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function.

Johansson P, Unge T, Cronin A, Arand M, Bergfors T, Jones TA, Mowbray SL. Johansson P, et al. Among authors: mowbray sl. J Mol Biol. 2005 Sep 2;351(5):1048-56. doi: 10.1016/j.jmb.2005.06.055. J Mol Biol. 2005. PMID: 16051262

9

Structural and functional studies of mycobacterial IspD enzymes.

Björkelid C, Bergfors T, Henriksson LM, Stern AL, Unge T, Mowbray SL, Jones TA. Björkelid C, et al. Among authors: mowbray sl. Acta Crystallogr D Biol Crystallogr. 2011 May;67(Pt 5):403-14. doi: 10.1107/S0907444911006160. Epub 2011 Apr 8. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 21543842

10

Synthesis and In Vitro Biological Evaluation of Quinolinyl Pyrimidines Targeting Type II NADH-Dehydrogenase (NDH-2).

Lu L, Åkerbladh L, Ahmad S, Konda V, Cao S, Vocat A, Maes L, Cole ST, Hughes D, Larhed M, Brandt P, Karlén A, Mowbray SL. Lu L, et al. Among authors: mowbray sl. ACS Infect Dis. 2022 Mar 11;8(3):482-498. doi: 10.1021/acsinfecdis.1c00413. Epub 2022 Feb 21. ACS Infect Dis. 2022. PMID: 35184552 Free PMC article.

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