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LKB1 loss is associated with glutathione deficiency under oxidative stress and sensitivity of cancer cells to cytotoxic drugs and γ-irradiation.
Zulato E, Ciccarese F, Agnusdei V, Pinazza M, Nardo G, Iorio E, Curtarello M, Silic-Benussi M, Rossi E, Venturoli C, Panieri E, Santoro MM, Di Paolo V, Quintieri L, Ciminale V, Indraccolo S. Zulato E, et al. Among authors: indraccolo s. Biochem Pharmacol. 2018 Oct;156:479-490. doi: 10.1016/j.bcp.2018.09.019. Epub 2018 Sep 15. Biochem Pharmacol. 2018. PMID: 30222967
mTOR inhibition downregulates glucose-6-phosphate dehydrogenase and induces ROS-dependent death in T-cell acute lymphoblastic leukemia cells.
Silic-Benussi M, Sharova E, Ciccarese F, Cavallari I, Raimondi V, Urso L, Corradin A, Kotler H, Scattolin G, Buldini B, Francescato S, Basso G, Minuzzo SA, Indraccolo S, D'Agostino DM, Ciminale V. Silic-Benussi M, et al. Among authors: indraccolo s. Redox Biol. 2022 May;51:102268. doi: 10.1016/j.redox.2022.102268. Epub 2022 Feb 24. Redox Biol. 2022. PMID: 35248829 Free PMC article.
Side population and cancer stem cells: therapeutic implications.
Moserle L, Ghisi M, Amadori A, Indraccolo S. Moserle L, et al. Among authors: indraccolo s. Cancer Lett. 2010 Feb 1;288(1):1-9. doi: 10.1016/j.canlet.2009.05.020. Epub 2009 Jun 11. Cancer Lett. 2010. PMID: 19523754 Review.
250 results