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Ketogenic diet administration later in life improves memory by modifying the synaptic cortical proteome via the PKA signaling pathway in aging mice.
Acuña-Catalán D, Shah S, Wehrfritz C, Nomura M, Acevedo A, Olmos C, Quiroz G, Huerta H, Bons J, Ampuero E, Wyneken U, Sanhueza M, Arancibia F, Contreras D, Cárdenas JC, Morales B, Schilling B, Newman JC, González-Billault C. Acuña-Catalán D, et al. Among authors: huerta h. Cell Rep Med. 2024 Jun 18;5(6):101593. doi: 10.1016/j.xcrm.2024.101593. Epub 2024 Jun 5. Cell Rep Med. 2024. PMID: 38843842 Free PMC article.
Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum-to-mitochondria Ca2+ transfer for survival.
Cardenas C, Lovy A, Silva-Pavez E, Urra F, Mizzoni C, Ahumada-Castro U, Bustos G, Jaňa F, Cruz P, Farias P, Mendoza E, Huerta H, Murgas P, Hunter M, Rios M, Cerda O, Georgakoudi I, Zakarian A, Molgó J, Foskett JK. Cardenas C, et al. Among authors: huerta h. Sci Signal. 2020 Jul 14;13(640):eaay1212. doi: 10.1126/scisignal.aay1212. Sci Signal. 2020. PMID: 32665411 Free PMC article.
The IP3R inhibitor desmethylxestospongin B reduces tumor cell migration, invasion and metastasis by impairing lysosome acidification and β1-integrin recycling.
Bustos G, Ahumada-Castro U, Silva-Pavez E, Huerta H, Puebla A, Quezada C, Morgado-Cáceres P, Casanova-Canelo C, Smith-Cortinez N, Podunavac M, Oyarce C, Lladser A, Farias P, Lovy A, Molgó J, Torres VA, Zakarian A, Cárdenas JC. Bustos G, et al. Among authors: huerta h. Biochim Biophys Acta Mol Basis Dis. 2025 Jan;1871(1):167557. doi: 10.1016/j.bbadis.2024.167557. Epub 2024 Oct 31. Biochim Biophys Acta Mol Basis Dis. 2025. PMID: 39486657 Free PMC article.
69 results