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Detectable FLT3-ITD or RAS mutation at the time of transformation from MDS to AML predicts for very poor outcomes.
Badar T, Patel KP, Thompson PA, DiNardo C, Takahashi K, Cabrero M, Borthakur G, Cortes J, Konopleva M, Kadia T, Bohannan Z, Pierce S, Jabbour EJ, Ravandi F, Daver N, Luthra R, Kantarjian H, Garcia-Manero G. Badar T, et al. Among authors: patel kp. Leuk Res. 2015 Dec;39(12):1367-74. doi: 10.1016/j.leukres.2015.10.005. Epub 2015 Oct 19. Leuk Res. 2015. PMID: 26547258 Free PMC article.
TP53 mutation is rare in primary myelofibrosis.
Greaves WO, Verma S, Bisrat T, Strati P, Rahimi H, Paladugu AV, Luthra R, Patel KP, Medeiros LJ, Yao H, Pierce S, Bueso-Ramos CE, Verstovsek S. Greaves WO, et al. Among authors: patel kp. Leuk Lymphoma. 2013 Jul;54(7):1552. doi: 10.3109/10428194.2012.745527. Epub 2012 Nov 30. Leuk Lymphoma. 2013. PMID: 23121011 No abstract available.
622 results