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Detectable FLT3-ITD or RAS mutation at the time of transformation from MDS to AML predicts for very poor outcomes.
Badar T, Patel KP, Thompson PA, DiNardo C, Takahashi K, Cabrero M, Borthakur G, Cortes J, Konopleva M, Kadia T, Bohannan Z, Pierce S, Jabbour EJ, Ravandi F, Daver N, Luthra R, Kantarjian H, Garcia-Manero G. Badar T, et al. Among authors: pierce s. Leuk Res. 2015 Dec;39(12):1367-74. doi: 10.1016/j.leukres.2015.10.005. Epub 2015 Oct 19. Leuk Res. 2015. PMID: 26547258 Free PMC article.
Outcome of patients with FLT3-mutated acute myeloid leukemia in first relapse.
Ravandi F, Kantarjian H, Faderl S, Garcia-Manero G, O'Brien S, Koller C, Pierce S, Brandt M, Kennedy D, Cortes J, Beran M. Ravandi F, et al. Among authors: pierce s. Leuk Res. 2010 Jun;34(6):752-6. doi: 10.1016/j.leukres.2009.10.001. Epub 2009 Oct 29. Leuk Res. 2010. PMID: 19878996 Free PMC article.
Persistence of cytogenetic abnormalities at complete remission after induction in patients with acute myeloid leukemia: prognostic significance and the potential role of allogeneic stem-cell transplantation.
Chen Y, Cortes J, Estrov Z, Faderl S, Qiao W, Abruzzo L, Garcia-Manero G, Pierce S, Huang X, Kebriaei P, Kadia T, De Lima M, Kantarjian H, Ravandi F. Chen Y, et al. Among authors: pierce s. J Clin Oncol. 2011 Jun 20;29(18):2507-13. doi: 10.1200/JCO.2010.34.2873. Epub 2011 May 9. J Clin Oncol. 2011. PMID: 21555694 Free PMC article. Clinical Trial.
1,414 results