Thorpe PE - Search Results

1

Tumor-specific targeting by Bavituximab, a phosphatidylserine-targeting monoclonal antibody with vascular targeting and immune modulating properties, in lung cancer xenografts.

Gerber DE, Hao G, Watkins L, Stafford JH, Anderson J, Holbein B, Öz OK, Mathews D, Thorpe PE, Hassan G, Kumar A, Brekken RA, Sun X. Gerber DE, et al. Among authors: thorpe pe. Am J Nucl Med Mol Imaging. 2015 Oct 12;5(5):493-503. eCollection 2015. Am J Nucl Med Mol Imaging. 2015. PMID: 26550540 Free PMC article.

2

Development of bavituximab, a vascular targeting agent with immune-modulating properties, for lung cancer treatment.

DeRose P, Thorpe PE, Gerber DE. DeRose P, et al. Among authors: thorpe pe. Immunotherapy. 2011 Aug;3(8):933-44. doi: 10.2217/imt.11.87. Immunotherapy. 2011. PMID: 21843081 Review.

3

Phase I safety and pharmacokinetic study of bavituximab, a chimeric phosphatidylserine-targeting monoclonal antibody, in patients with advanced solid tumors.

Gerber DE, Stopeck AT, Wong L, Rosen LS, Thorpe PE, Shan JS, Ibrahim NK. Gerber DE, et al. Among authors: thorpe pe. Clin Cancer Res. 2011 Nov 1;17(21):6888-96. doi: 10.1158/1078-0432.CCR-11-1074. Epub 2011 Oct 11. Clin Cancer Res. 2011. PMID: 21989064 Clinical Trial.

4

Near-infrared Optical Imaging of Exposed Phosphatidylserine in a Mouse Glioma Model.

Zhao D, Stafford JH, Zhou H, Thorpe PE. Zhao D, et al. Among authors: thorpe pe. Transl Oncol. 2011 Dec;4(6):355-64. doi: 10.1593/tlo.11178. Epub 2011 Dec 1. Transl Oncol. 2011. PMID: 22191000 Free PMC article.

5

Highly specific PET imaging of prostate tumors in mice with an iodine-124-labeled antibody fragment that targets phosphatidylserine.

Stafford JH, Hao G, Best AM, Sun X, Thorpe PE. Stafford JH, et al. Among authors: thorpe pe. PLoS One. 2013 Dec 19;8(12):e84864. doi: 10.1371/journal.pone.0084864. eCollection 2013. PLoS One. 2013. PMID: 24367699 Free PMC article.

6

Antibody-Mediated Blockade of Phosphatidylserine Enhances the Antitumor Effect of Sorafenib in Hepatocellular Carcinomas Xenografts.

Cheng X, Li L, Thorpe PE, Yopp AC, Brekken RA, Huang X. Cheng X, et al. Among authors: thorpe pe. Ann Surg Oncol. 2016 Dec;23(Suppl 5):583-591. doi: 10.1245/s10434-016-5107-5. Epub 2016 Feb 4. Ann Surg Oncol. 2016. PMID: 26847681 Clinical Trial.

7

Increased exposure of phosphatidylethanolamine on the surface of tumor vascular endothelium.

Stafford JH, Thorpe PE. Stafford JH, et al. Among authors: thorpe pe. Neoplasia. 2011 Apr;13(4):299-308. doi: 10.1593/neo.101366. Neoplasia. 2011. PMID: 21472134 Free PMC article.

8

Combination of a monoclonal anti-phosphatidylserine antibody with gemcitabine strongly inhibits the growth and metastasis of orthotopic pancreatic tumors in mice.

Beck AW, Luster TA, Miller AF, Holloway SE, Conner CR, Barnett CC, Thorpe PE, Fleming JB, Brekken RA. Beck AW, et al. Among authors: thorpe pe. Int J Cancer. 2006 May 15;118(10):2639-43. doi: 10.1002/ijc.21684. Int J Cancer. 2006. PMID: 16353142

9

Antiphosphatidylserine antibody combined with irradiation damages tumor blood vessels and induces tumor immunity in a rat model of glioblastoma.

He J, Yin Y, Luster TA, Watkins L, Thorpe PE. He J, et al. Among authors: thorpe pe. Clin Cancer Res. 2009 Nov 15;15(22):6871-80. doi: 10.1158/1078-0432.CCR-09-1499. Epub 2009 Nov 3. Clin Cancer Res. 2009. PMID: 19887482

10

Vascular endothelial growth factor as a marker of tumor endothelium.

Brekken RA, Huang X, King SW, Thorpe PE. Brekken RA, et al. Among authors: thorpe pe. Cancer Res. 1998 May 1;58(9):1952-9. Cancer Res. 1998. PMID: 9581838

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