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Page 1
Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques.
Micci L, Ryan ES, Fromentin R, Bosinger SE, Harper JL, He T, Paganini S, Easley KA, Chahroudi A, Benne C, Gumber S, McGary CS, Rogers KA, Deleage C, Lucero C, Byrareddy SN, Apetrei C, Estes JD, Lifson JD, Piatak M Jr, Chomont N, Villinger F, Silvestri G, Brenchley JM, Paiardini M. Micci L, et al. Among authors: villinger f. J Clin Invest. 2015 Dec;125(12):4497-513. doi: 10.1172/JCI81400. Epub 2015 Nov 9. J Clin Invest. 2015. PMID: 26551680 Free PMC article.
Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys.
Klatt NR, Villinger F, Bostik P, Gordon SN, Pereira L, Engram JC, Mayne A, Dunham RM, Lawson B, Ratcliffe SJ, Sodora DL, Else J, Reimann K, Staprans SI, Haase AT, Estes JD, Silvestri G, Ansari AA. Klatt NR, et al. Among authors: villinger f. J Clin Invest. 2008 Jun;118(6):2039-49. doi: 10.1172/JCI33814. J Clin Invest. 2008. PMID: 18497876 Free PMC article.
Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection.
Eberly MD, Kader M, Hassan W, Rogers KA, Zhou J, Mueller YM, Mattapallil MJ, Piatak M Jr, Lifson JD, Katsikis PD, Roederer M, Villinger F, Mattapallil JJ. Eberly MD, et al. Among authors: villinger f. J Immunol. 2009 Feb 1;182(3):1439-48. doi: 10.4049/jimmunol.182.3.1439. J Immunol. 2009. PMID: 19155491 Free PMC article.
Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.
Okoye A, Park H, Rohankhedkar M, Coyne-Johnson L, Lum R, Walker JM, Planer SL, Legasse AW, Sylwester AW, Piatak M Jr, Lifson JD, Sodora DL, Villinger F, Axthelm MK, Schmitz JE, Picker LJ. Okoye A, et al. Among authors: villinger f. J Exp Med. 2009 Jul 6;206(7):1575-88. doi: 10.1084/jem.20090356. Epub 2009 Jun 22. J Exp Med. 2009. PMID: 19546246 Free PMC article.
Increased CD4+ T cell levels during IL-7 administration of antiretroviral therapy-treated simian immunodeficiency virus-positive macaques are not dependent on strong proliferative responses.
Leone A, Rohankhedkar M, Okoye A, Legasse A, Axthelm MK, Villinger F, Piatak M Jr, Lifson JD, Assouline B, Morre M, Picker LJ, Sodora DL. Leone A, et al. Among authors: villinger f. J Immunol. 2010 Aug 1;185(3):1650-9. doi: 10.4049/jimmunol.0902626. Epub 2010 Jul 9. J Immunol. 2010. PMID: 20622118 Free PMC article.
Interleukin-21 administration to rhesus macaques chronically infected with simian immunodeficiency virus increases cytotoxic effector molecules in T cells and NK cells and enhances B cell function without increasing immune activation or viral replication.
Pallikkuth S, Rogers K, Villinger F, Dosterii M, Vaccari M, Franchini G, Pahwa R, Pahwa S. Pallikkuth S, et al. Among authors: villinger f. Vaccine. 2011 Nov 15;29(49):9229-38. doi: 10.1016/j.vaccine.2011.09.118. Epub 2011 Oct 11. Vaccine. 2011. PMID: 21996099 Free PMC article.
322 results