Kurtoglu M - Search Results

1

The role of hypoxia in pancreatic cancer: a potential therapeutic target?

Erkan M, Kurtoglu M, Kleeff J. Erkan M, et al. Among authors: kurtoglu m. Expert Rev Gastroenterol Hepatol. 2016;10(3):301-16. doi: 10.1586/17474124.2016.1117386. Epub 2015 Nov 27. Expert Rev Gastroenterol Hepatol. 2016. PMID: 26560854 Review.

2

Engineering human stellate cells for beta cell replacement therapy promotes in vivo recruitment of regulatory T cells.

Oran DC, Lokumcu T, Inceoglu Y, Akolpoglu MB, Albayrak O, Bal T, Kurtoglu M, Erkan M, Can F, Bagci-Onder T, Kizilel S. Oran DC, et al. Among authors: kurtoglu m. Mater Today Bio. 2019 May 23;2:100006. doi: 10.1016/j.mtbio.2019.100006. eCollection 2019 Mar. Mater Today Bio. 2019. PMID: 32159143 Free PMC article.

3

Intrinsically lower AKT, mammalian target of rapamycin, and hypoxia-inducible factor activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia in lung cancer cell lines.

Wangpaichitr M, Savaraj N, Maher J, Kurtoglu M, Lampidis TJ. Wangpaichitr M, et al. Among authors: kurtoglu m. Mol Cancer Ther. 2008 Jun;7(6):1506-13. doi: 10.1158/1535-7163.MCT-07-2334. Mol Cancer Ther. 2008. PMID: 18566221 Free PMC article.

4

From delocalized lipophilic cations to hypoxia: blocking tumor cell mitochondrial function leads to therapeutic gain with glycolytic inhibitors.

Kurtoglu M, Lampidis TJ. Kurtoglu M, et al. Mol Nutr Food Res. 2009 Jan;53(1):68-75. doi: 10.1002/mnfr.200700457. Mol Nutr Food Res. 2009. PMID: 19072739 Free PMC article. Review.

5

Hypoxia-inducible factor-1 confers resistance to the glycolytic inhibitor 2-deoxy-D-glucose.

Maher JC, Wangpaichitr M, Savaraj N, Kurtoglu M, Lampidis TJ. Maher JC, et al. Among authors: kurtoglu m. Mol Cancer Ther. 2007 Feb;6(2):732-41. doi: 10.1158/1535-7163.MCT-06-0407. Mol Cancer Ther. 2007. PMID: 17308069

6

Differential toxic mechanisms of 2-deoxy-D-glucose versus 2-fluorodeoxy-D-glucose in hypoxic and normoxic tumor cells.

Kurtoglu M, Maher JC, Lampidis TJ. Kurtoglu M, et al. Antioxid Redox Signal. 2007 Sep;9(9):1383-90. doi: 10.1089/ars.2007.1714. Antioxid Redox Signal. 2007. PMID: 17627467 Review.

7

Under normoxia, 2-deoxy-D-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation.

Kurtoglu M, Gao N, Shang J, Maher JC, Lehrman MA, Wangpaichitr M, Savaraj N, Lane AN, Lampidis TJ. Kurtoglu M, et al. Mol Cancer Ther. 2007 Nov;6(11):3049-58. doi: 10.1158/1535-7163.MCT-07-0310. Mol Cancer Ther. 2007. PMID: 18025288

8

2-Deoxy-D-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion.

Xi H, Kurtoglu M, Liu H, Wangpaichitr M, You M, Liu X, Savaraj N, Lampidis TJ. Xi H, et al. Among authors: kurtoglu m. Cancer Chemother Pharmacol. 2011 Apr;67(4):899-910. doi: 10.1007/s00280-010-1391-0. Epub 2010 Jul 1. Cancer Chemother Pharmacol. 2011. PMID: 20593179 Free PMC article.

9

Increased sensitivity to glucose starvation correlates with downregulation of glycogen phosphorylase isoform PYGB in tumor cell lines resistant to 2-deoxy-D-glucose.

Philips KB, Kurtoglu M, Leung HJ, Liu H, Gao N, Lehrman MA, Murray TG, Lampidis TJ. Philips KB, et al. Among authors: kurtoglu m. Cancer Chemother Pharmacol. 2014 Feb;73(2):349-61. doi: 10.1007/s00280-013-2358-8. Epub 2013 Dec 1. Cancer Chemother Pharmacol. 2014. PMID: 24292700 Free PMC article.

10

Targeting cisplatin-resistant human tumor cells with metabolic inhibitors.

Sullivan EJ, Kurtoglu M, Brenneman R, Liu H, Lampidis TJ. Sullivan EJ, et al. Among authors: kurtoglu m. Cancer Chemother Pharmacol. 2014 Feb;73(2):417-27. doi: 10.1007/s00280-013-2366-8. Epub 2013 Dec 19. Cancer Chemother Pharmacol. 2014. PMID: 24352250

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