Sawyers CL - Search Results

1

Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer.

Watson PA, Arora VK, Sawyers CL. Watson PA, et al. Among authors: sawyers cl. Nat Rev Cancer. 2015 Dec;15(12):701-11. doi: 10.1038/nrc4016. Epub 2015 Nov 13. Nat Rev Cancer. 2015. PMID: 26563462 Free PMC article. Review.

2

Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis.

Scher HI, Sawyers CL. Scher HI, et al. Among authors: sawyers cl. J Clin Oncol. 2005 Nov 10;23(32):8253-61. doi: 10.1200/JCO.2005.03.4777. J Clin Oncol. 2005. PMID: 16278481 Review.

3

Context-dependent hormone-refractory progression revealed through characterization of a novel murine prostate cancer cell line.

Watson PA, Ellwood-Yen K, King JC, Wongvipat J, Lebeau MM, Sawyers CL. Watson PA, et al. Among authors: sawyers cl. Cancer Res. 2005 Dec 15;65(24):11565-71. doi: 10.1158/0008-5472.CAN-05-3441. Cancer Res. 2005. PMID: 16357166

4

Murine cell lines derived from Pten null prostate cancer show the critical role of PTEN in hormone refractory prostate cancer development.

Jiao J, Wang S, Qiao R, Vivanco I, Watson PA, Sawyers CL, Wu H. Jiao J, et al. Among authors: sawyers cl. Cancer Res. 2007 Jul 1;67(13):6083-91. doi: 10.1158/0008-5472.CAN-06-4202. Cancer Res. 2007. PMID: 17616663

5

The cancer biomarker problem.

Sawyers CL. Sawyers CL. Nature. 2008 Apr 3;452(7187):548-52. doi: 10.1038/nature06913. Nature. 2008. PMID: 18385728 Review.

6

Targeting the androgen receptor pathway in prostate cancer.

Chen Y, Sawyers CL, Scher HI. Chen Y, et al. Among authors: sawyers cl. Curr Opin Pharmacol. 2008 Aug;8(4):440-8. doi: 10.1016/j.coph.2008.07.005. Epub 2008 Aug 12. Curr Opin Pharmacol. 2008. PMID: 18674639 Free PMC article. Review.

7

The nuclear factor-kappaB pathway controls the progression of prostate cancer to androgen-independent growth.

Jin RJ, Lho Y, Connelly L, Wang Y, Yu X, Saint Jean L, Case TC, Ellwood-Yen K, Sawyers CL, Bhowmick NA, Blackwell TS, Yull FE, Matusik RJ. Jin RJ, et al. Among authors: sawyers cl. Cancer Res. 2008 Aug 15;68(16):6762-9. doi: 10.1158/0008-5472.CAN-08-0107. Cancer Res. 2008. PMID: 18701501 Free PMC article.

8

Histone deacetylases are required for androgen receptor function in hormone-sensitive and castrate-resistant prostate cancer.

Welsbie DS, Xu J, Chen Y, Borsu L, Scher HI, Rosen N, Sawyers CL. Welsbie DS, et al. Among authors: sawyers cl. Cancer Res. 2009 Feb 1;69(3):958-66. doi: 10.1158/0008-5472.CAN-08-2216. Epub 2009 Jan 27. Cancer Res. 2009. PMID: 19176386 Free PMC article.

9

Development of a second-generation antiandrogen for treatment of advanced prostate cancer.

Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, Wongvipat J, Smith-Jones PM, Yoo D, Kwon A, Wasielewska T, Welsbie D, Chen CD, Higano CS, Beer TM, Hung DT, Scher HI, Jung ME, Sawyers CL. Tran C, et al. Among authors: sawyers cl. Science. 2009 May 8;324(5928):787-90. doi: 10.1126/science.1168175. Epub 2009 Apr 9. Science. 2009. PMID: 19359544 Free PMC article. Clinical Trial.

10

Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study.

Scher HI, Beer TM, Higano CS, Anand A, Taplin ME, Efstathiou E, Rathkopf D, Shelkey J, Yu EY, Alumkal J, Hung D, Hirmand M, Seely L, Morris MJ, Danila DC, Humm J, Larson S, Fleisher M, Sawyers CL; Prostate Cancer Foundation/Department of Defense Prostate Cancer Clinical Trials Consortium. Scher HI, et al. Among authors: sawyers cl. Lancet. 2010 Apr 24;375(9724):1437-46. doi: 10.1016/S0140-6736(10)60172-9. Epub 2010 Apr 14. Lancet. 2010. PMID: 20398925 Free PMC article. Clinical Trial.

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