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Page 1
Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Terminal Differentiation of Human B Cells into Plasma Cells.
Caron G, Hussein M, Kulis M, Delaloy C, Chatonnet F, Pignarre A, Avner S, Lemarié M, Mahé EA, Verdaguer-Dot N, Queirós AC, Tarte K, Martín-Subero JI, Salbert G, Fest T. Caron G, et al. Among authors: pignarre a. Cell Rep. 2015 Nov 3;13(5):1059-71. doi: 10.1016/j.celrep.2015.09.051. Epub 2015 Oct 22. Cell Rep. 2015. PMID: 26565917 Free article.
Committed Human CD23-Negative Light-Zone Germinal Center B Cells Delineate Transcriptional Program Supporting Plasma Cell Differentiation.
Santamaria K, Desmots F, Leonard S, Caron G, Haas M, Delaloy C, Chatonnet F, Rossille D, Pignarre A, Monvoisin C, Seffals M, Lamaison C, Cogné M, Tarte K, Fest T. Santamaria K, et al. Among authors: pignarre a. Front Immunol. 2021 Dec 2;12:744573. doi: 10.3389/fimmu.2021.744573. eCollection 2021. Front Immunol. 2021. PMID: 34925321 Free PMC article.
PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma.
Haas M, Caron G, Chatonnet F, Manenti S, Alaterre E, Devin J, Delaloy C, Bertolin G, Viel R, Pignarre A, Llamas-Gutierrez F, Marchalot A, Decaux O, Tarte K, Delpy L, Moreaux J, Fest T. Haas M, et al. Among authors: pignarre a. Blood. 2022 Apr 14;139(15):2316-2337. doi: 10.1182/blood.2021014011. Blood. 2022. PMID: 35108359 Free article.
The hydroxymethylome of multiple myeloma identifies FAM72D as a 1q21 marker linked to proliferation.
Chatonnet F, Pignarre A, Sérandour AA, Caron G, Avner S, Robert N, Kassambara A, Laurent A, Bizot M, Agirre X, Prosper F, Martin-Subero JI, Moreaux J, Fest T, Salbert G. Chatonnet F, et al. Among authors: pignarre a. Haematologica. 2020 Mar;105(3):774-783. doi: 10.3324/haematol.2019.222133. Epub 2019 Jun 20. Haematologica. 2020. PMID: 31221779 Free PMC article.
Locus suicide recombination actively occurs on the functionally rearranged IgH allele in B-cells from inflamed human lymphoid tissues.
Dalloul I, Boyer F, Dalloul Z, Pignarre A, Caron G, Fest T, Chatonnet F, Delaloy C, Durandy A, Jeannet R, Lereclus E, Boutouil H, Aldigier JC, Péron S, Le Noir S, Cook-Moreau J, Cogné M. Dalloul I, et al. Among authors: pignarre a. PLoS Genet. 2019 Jun 14;15(6):e1007721. doi: 10.1371/journal.pgen.1007721. eCollection 2019 Jun. PLoS Genet. 2019. PMID: 31199803 Free PMC article.