Abankwa D - Search Results

1

Phenotypic Screening Identifies Protein Synthesis Inhibitors as H-Ras-Nanocluster-Increasing Tumor Growth Inducers.

Najumudeen AK, Posada IM, Lectez B, Zhou Y, Landor SK, Fallarero A, Vuorela P, Hancock J, Abankwa D. Najumudeen AK, et al. Among authors: abankwa d. Biochemistry. 2015 Dec 15;54(49):7212-21. doi: 10.1021/acs.biochem.5b00724. Epub 2015 Nov 30. Biochemistry. 2015. PMID: 26568031

2

Structure and dynamics of the full-length lipid-modified H-Ras protein in a 1,2-dimyristoylglycero-3-phosphocholine bilayer.

Gorfe AA, Hanzal-Bayer M, Abankwa D, Hancock JF, McCammon JA. Gorfe AA, et al. Among authors: abankwa d. J Med Chem. 2007 Feb 22;50(4):674-84. doi: 10.1021/jm061053f. Epub 2007 Jan 31. J Med Chem. 2007. PMID: 17263520

3

Ras nanoclusters: molecular structure and assembly.

Abankwa D, Gorfe AA, Hancock JF. Abankwa D, et al. Semin Cell Dev Biol. 2007 Oct;18(5):599-607. doi: 10.1016/j.semcdb.2007.08.003. Epub 2007 Aug 19. Semin Cell Dev Biol. 2007. PMID: 17897845 Free PMC article. Review.

4

A novel switch region regulates H-ras membrane orientation and signal output.

Abankwa D, Hanzal-Bayer M, Ariotti N, Plowman SJ, Gorfe AA, Parton RG, McCammon JA, Hancock JF. Abankwa D, et al. EMBO J. 2008 Mar 5;27(5):727-35. doi: 10.1038/emboj.2008.10. Epub 2008 Feb 14. EMBO J. 2008. PMID: 18273062 Free PMC article.

5

Mechanisms of Ras membrane organization and signalling: Ras on a rocker.

Abankwa D, Gorfe AA, Hancock JF. Abankwa D, et al. Cell Cycle. 2008 Sep 1;7(17):2667-73. doi: 10.4161/cc.7.17.6596. Epub 2008 Sep 28. Cell Cycle. 2008. PMID: 18758236 Free PMC article.

6

Ras membrane orientation and nanodomain localization generate isoform diversity.

Abankwa D, Gorfe AA, Inder K, Hancock JF. Abankwa D, et al. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1130-5. doi: 10.1073/pnas.0903907107. Epub 2010 Jan 4. Proc Natl Acad Sci U S A. 2010. PMID: 20080631 Free PMC article.

7

An N-terminal polybasic motif of Gαq is required for signaling and influences membrane nanodomain distribution.

Crouthamel M, Abankwa D, Zhang L, DiLizio C, Manning DR, Hancock JF, Wedegaertner PB. Crouthamel M, et al. Among authors: abankwa d. Mol Pharmacol. 2010 Oct;78(4):767-77. doi: 10.1124/mol.110.066340. Epub 2010 Jul 27. Mol Pharmacol. 2010. PMID: 20664004 Free PMC article.

8

Cellular FRET-Biosensors to Detect Membrane Targeting Inhibitors of N-Myristoylated Proteins.

Najumudeen AK, Köhnke M, Solman M, Alexandrov K, Abankwa D. Najumudeen AK, et al. Among authors: abankwa d. PLoS One. 2013 Jun 18;8(6):e66425. doi: 10.1371/journal.pone.0066425. Print 2013. PLoS One. 2013. PMID: 23824448 Free PMC article.

9

Nanoclustering and heterogeneous membrane diffusion of Ras studied by FRAP and RICS analysis.

Guzmán C, Solman M, Abankwa D. Guzmán C, et al. Among authors: abankwa d. Methods Mol Biol. 2014;1120:307-26. doi: 10.1007/978-1-62703-791-4_20. Methods Mol Biol. 2014. PMID: 24470034

10

The efficacy of Raf kinase recruitment to the GTPase H-ras depends on H-ras membrane conformer-specific nanoclustering.

Guzmán C, Šolman M, Ligabue A, Blaževitš O, Andrade DM, Reymond L, Eggeling C, Abankwa D. Guzmán C, et al. Among authors: abankwa d. J Biol Chem. 2014 Apr 4;289(14):9519-33. doi: 10.1074/jbc.M113.537001. Epub 2014 Feb 25. J Biol Chem. 2014. PMID: 24569991 Free PMC article.

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