Buffering properties of cationic polymethacrylates are not the only key to successful gene delivery.
Dubruel P, Christiaens B, Rosseneu M, Vandekerckhove J, Grooten J, Goossens V, Schacht E.
Dubruel P, et al.
Biomacromolecules. 2004 Mar-Apr;5(2):379-88. doi: 10.1021/bm034438d.
Biomacromolecules. 2004.
PMID: 15002997
Recently, we have shown that polymethacrylates containing imidazole side groups (HYMIMMA) or acid functions (MA), which have similar buffering properties as polyethyleneimine, were not able to transfect Cos-1 cells, whereas polymers containing only tertiary amines (DMAEMA) do tra …
Recently, we have shown that polymethacrylates containing imidazole side groups (HYMIMMA) or acid functions (MA), which have similar bufferi …