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Role of necroptosis in the pathogenesis of solid organ injury.
Zhao H, Jaffer T, Eguchi S, Wang Z, Linkermann A, Ma D. Zhao H, et al. Among authors: linkermann a. Cell Death Dis. 2015 Nov 19;6(11):e1975. doi: 10.1038/cddis.2015.316. Cell Death Dis. 2015. PMID: 26583318 Free PMC article. Review.
Efficacy of finerenone in patients with type 2 diabetes, chronic kidney disease and altered markers of liver steatosis and fibrosis: A FIDELITY subgroup analysis.
Perakakis N, Bornstein SR, Birkenfeld AL, Linkermann A, Demir M, Anker SD, Filippatos G, Pitt B, Rossing P, Ruilope LM, Kolkhof P, Lawatscheck R, Scott C, Bakris GL; FIDELIO-DKD and FIGARO-DKD investigators. Perakakis N, et al. Among authors: linkermann a. Diabetes Obes Metab. 2024 Jan;26(1):191-200. doi: 10.1111/dom.15305. Epub 2023 Oct 10. Diabetes Obes Metab. 2024. PMID: 37814928
Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury.
Linkermann A, Bräsen JH, Darding M, Jin MK, Sanz AB, Heller JO, De Zen F, Weinlich R, Ortiz A, Walczak H, Weinberg JM, Green DR, Kunzendorf U, Krautwald S. Linkermann A, et al. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12024-9. doi: 10.1073/pnas.1305538110. Epub 2013 Jul 1. Proc Natl Acad Sci U S A. 2013. PMID: 23818611 Free PMC article.
Necroptosis in immunity and ischemia-reperfusion injury.
Linkermann A, Hackl MJ, Kunzendorf U, Walczak H, Krautwald S, Jevnikar AM. Linkermann A, et al. Am J Transplant. 2013 Nov;13(11):2797-804. doi: 10.1111/ajt.12448. Epub 2013 Sep 18. Am J Transplant. 2013. PMID: 24103029 Free article. Review.
Widespread mitochondrial depletion via mitophagy does not compromise necroptosis.
Tait SW, Oberst A, Quarato G, Milasta S, Haller M, Wang R, Karvela M, Ichim G, Yatim N, Albert ML, Kidd G, Wakefield R, Frase S, Krautwald S, Linkermann A, Green DR. Tait SW, et al. Among authors: linkermann a. Cell Rep. 2013 Nov 27;5(4):878-85. doi: 10.1016/j.celrep.2013.10.034. Epub 2013 Nov 21. Cell Rep. 2013. PMID: 24268776 Free PMC article.
Necroptosis.
Linkermann A, Green DR. Linkermann A, et al. N Engl J Med. 2014 Jan 30;370(5):455-65. doi: 10.1056/NEJMra1310050. N Engl J Med. 2014. PMID: 24476434 Free PMC article. Review. No abstract available.
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis.
Fauster A, Rebsamen M, Huber KV, Bigenzahn JW, Stukalov A, Lardeau CH, Scorzoni S, Bruckner M, Gridling M, Parapatics K, Colinge J, Bennett KL, Kubicek S, Krautwald S, Linkermann A, Superti-Furga G. Fauster A, et al. Among authors: linkermann a. Cell Death Dis. 2015 May 21;6(5):e1767. doi: 10.1038/cddis.2015.130. Cell Death Dis. 2015. PMID: 25996294 Free PMC article.
The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance.
Gautheron J, Vucur M, Schneider AT, Severi I, Roderburg C, Roy S, Bartneck M, Schrammen P, Diaz MB, Ehling J, Gremse F, Heymann F, Koppe C, Lammers T, Kiessling F, Van Best N, Pabst O, Courtois G, Linkermann A, Krautwald S, Neumann UP, Tacke F, Trautwein C, Green DR, Longerich T, Frey N, Luedde M, Bluher M, Herzig S, Heikenwalder M, Luedde T. Gautheron J, et al. Among authors: linkermann a. Nat Commun. 2016 Jun 21;7:11869. doi: 10.1038/ncomms11869. Nat Commun. 2016. PMID: 27323669 Free PMC article.
154 results