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Synthetic CRISPR RNA-Cas9-guided genome editing in human cells.
Rahdar M, McMahon MA, Prakash TP, Swayze EE, Bennett CF, Cleveland DW. Rahdar M, et al. Among authors: bennett cf. Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):E7110-7. doi: 10.1073/pnas.1520883112. Epub 2015 Nov 16. Proc Natl Acad Sci U S A. 2015. PMID: 26589814 Free PMC article.
Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase.
Eldrup AB, Allerson CR, Bennett CF, Bera S, Bhat B, Bhat N, Bosserman MR, Brooks J, Burlein C, Carroll SS, Cook PD, Getty KL, MacCoss M, McMasters DR, Olsen DB, Prakash TP, Prhavc M, Song Q, Tomassini JE, Xia J. Eldrup AB, et al. Among authors: bennett cf. J Med Chem. 2004 Apr 22;47(9):2283-95. doi: 10.1021/jm030424e. J Med Chem. 2004. PMID: 15084127
Structure-activity relationship of heterobase-modified 2'-C-methyl ribonucleosides as inhibitors of hepatitis C virus RNA replication.
Eldrup AB, Prhavc M, Brooks J, Bhat B, Prakash TP, Song Q, Bera S, Bhat N, Dande P, Cook PD, Bennett CF, Carroll SS, Ball RG, Bosserman M, Burlein C, Colwell LF, Fay JF, Flores OA, Getty K, LaFemina RL, Leone J, MacCoss M, McMasters DR, Tomassini JE, Von Langen D, Wolanski B, Olsen DB. Eldrup AB, et al. Among authors: bennett cf. J Med Chem. 2004 Oct 7;47(21):5284-97. doi: 10.1021/jm040068f. J Med Chem. 2004. PMID: 15456273
Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid.
Albertshofer K, Siwkowski AM, Wancewicz EV, Esau CC, Watanabe T, Nishihara KC, Kinberger GA, Malik L, Eldrup AB, Manoharan M, Geary RS, Monia BP, Swayze EE, Griffey RH, Bennett CF, Maier MA. Albertshofer K, et al. Among authors: bennett cf. J Med Chem. 2005 Oct 20;48(21):6741-9. doi: 10.1021/jm050490b. J Med Chem. 2005. PMID: 16220989
Antisense oligonucleotide therapy for neurodegenerative disease.
Smith RA, Miller TM, Yamanaka K, Monia BP, Condon TP, Hung G, Lobsiger CS, Ward CM, McAlonis-Downes M, Wei H, Wancewicz EV, Bennett CF, Cleveland DW. Smith RA, et al. Among authors: bennett cf. J Clin Invest. 2006 Aug;116(8):2290-6. doi: 10.1172/JCI25424. Epub 2006 Jul 27. J Clin Invest. 2006. PMID: 16878173 Free PMC article.
Potent inhibition of microRNA in vivo without degradation.
Davis S, Propp S, Freier SM, Jones LE, Serra MJ, Kinberger G, Bhat B, Swayze EE, Bennett CF, Esau C. Davis S, et al. Among authors: bennett cf. Nucleic Acids Res. 2009 Jan;37(1):70-7. doi: 10.1093/nar/gkn904. Epub 2008 Nov 16. Nucleic Acids Res. 2009. PMID: 19015151 Free PMC article.
Peptide nucleic acids conjugated to short basic peptides show improved pharmacokinetics and antisense activity in adipose tissue.
Wancewicz EV, Maier MA, Siwkowski AM, Albertshofer K, Winger TM, Berdeja A, Gaus H, Vickers TA, Bennett CF, Monia BP, Griffey RH, Nulf CJ, Hu J, Corey DR, Swayze EE, Kinberger GA. Wancewicz EV, et al. Among authors: bennett cf. J Med Chem. 2010 May 27;53(10):3919-26. doi: 10.1021/jm901489k. J Med Chem. 2010. PMID: 20420385 Free PMC article.
285 results