Swayze EE - Search Results

1

Synthetic CRISPR RNA-Cas9-guided genome editing in human cells.

Rahdar M, McMahon MA, Prakash TP, Swayze EE, Bennett CF, Cleveland DW. Rahdar M, et al. Among authors: swayze ee. Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):E7110-7. doi: 10.1073/pnas.1520883112. Epub 2015 Nov 16. Proc Natl Acad Sci U S A. 2015. PMID: 26589814 Free PMC article.

2

Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA.

Allerson CR, Sioufi N, Jarres R, Prakash TP, Naik N, Berdeja A, Wanders L, Griffey RH, Swayze EE, Bhat B. Allerson CR, et al. Among authors: swayze ee. J Med Chem. 2005 Feb 24;48(4):901-4. doi: 10.1021/jm049167j. J Med Chem. 2005. PMID: 15715458

3

Positional effect of chemical modifications on short interference RNA activity in mammalian cells.

Prakash TP, Allerson CR, Dande P, Vickers TA, Sioufi N, Jarres R, Baker BF, Swayze EE, Griffey RH, Bhat B. Prakash TP, et al. Among authors: swayze ee. J Med Chem. 2005 Jun 30;48(13):4247-53. doi: 10.1021/jm050044o. J Med Chem. 2005. PMID: 15974578

4

Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid.

Albertshofer K, Siwkowski AM, Wancewicz EV, Esau CC, Watanabe T, Nishihara KC, Kinberger GA, Malik L, Eldrup AB, Manoharan M, Geary RS, Monia BP, Swayze EE, Griffey RH, Bennett CF, Maier MA. Albertshofer K, et al. Among authors: swayze ee. J Med Chem. 2005 Oct 20;48(21):6741-9. doi: 10.1021/jm050490b. J Med Chem. 2005. PMID: 16220989

5

Improving RNA interference in mammalian cells by 4'-thio-modified small interfering RNA (siRNA): effect on siRNA activity and nuclease stability when used in combination with 2'-O-alkyl modifications.

Dande P, Prakash TP, Sioufi N, Gaus H, Jarres R, Berdeja A, Swayze EE, Griffey RH, Bhat B. Dande P, et al. Among authors: swayze ee. J Med Chem. 2006 Mar 9;49(5):1624-34. doi: 10.1021/jm050822c. J Med Chem. 2006. PMID: 16509579

6

Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids.

Maier MA, Esau CC, Siwkowski AM, Wancewicz EV, Albertshofer K, Kinberger GA, Kadaba NS, Watanabe T, Manoharan M, Bennett CF, Griffey RH, Swayze EE. Maier MA, et al. Among authors: swayze ee. J Med Chem. 2006 Apr 20;49(8):2534-42. doi: 10.1021/jm051275y. J Med Chem. 2006. PMID: 16610796

7

RNA interference by 2',5'-linked nucleic acid duplexes in mammalian cells.

Prakash TP, Kraynack B, Baker BF, Swayze EE, Bhat B. Prakash TP, et al. Among authors: swayze ee. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3238-40. doi: 10.1016/j.bmcl.2006.03.053. Epub 2006 Apr 17. Bioorg Med Chem Lett. 2006. PMID: 16616491

8

Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals.

Swayze EE, Siwkowski AM, Wancewicz EV, Migawa MT, Wyrzykiewicz TK, Hung G, Monia BP, Bennett CF. Swayze EE, et al. Nucleic Acids Res. 2007;35(2):687-700. doi: 10.1093/nar/gkl1071. Epub 2006 Dec 19. Nucleic Acids Res. 2007. PMID: 17182632 Free PMC article.

9

Design, synthesis and evaluation of constrained methoxyethyl (cMOE) and constrained ethyl (cEt) nucleoside analogs.

Seth PP, Siwkowski A, Allerson CR, Vasquez G, Lee S, Prakash TP, Kinberger G, Migawa MT, Gaus H, Bhat B, Swayze EE. Seth PP, et al. Among authors: swayze ee. Nucleic Acids Symp Ser (Oxf). 2008;(52):553-4. doi: 10.1093/nass/nrn280. Nucleic Acids Symp Ser (Oxf). 2008. PMID: 18776499

10

Potent inhibition of microRNA in vivo without degradation.

Davis S, Propp S, Freier SM, Jones LE, Serra MJ, Kinberger G, Bhat B, Swayze EE, Bennett CF, Esau C. Davis S, et al. Among authors: swayze ee. Nucleic Acids Res. 2009 Jan;37(1):70-7. doi: 10.1093/nar/gkn904. Epub 2008 Nov 16. Nucleic Acids Res. 2009. PMID: 19015151 Free PMC article.

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