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Novel working hypothesis for pathogenesis of hematological malignancies: combination of mutations-induced cellular phenotypes determines the disease (cMIP-DD).
Kitamura T, Watanabe-Okochi N, Enomoto Y, Nakahara F, Oki T, Komeno Y, Kato N, Doki N, Uchida T, Kagiyama Y, Togami K, Kawabata KC, Nishimura K, Hayashi Y, Nagase R, Saika M, Fukushima T, Asada S, Fujino T, Izawa Y, Horikawa S, Fukuyama T, Tanaka Y, Ono R, Goyama S, Nosaka T, Kitaura J, Inoue D. Kitamura T, et al. J Biochem. 2016 Jan;159(1):17-25. doi: 10.1093/jb/mvv114. Epub 2015 Nov 20. J Biochem. 2016. PMID: 26590301 Free PMC article. Review.
AML1 mutations induced MDS and MDS/AML in a mouse BMT model.
Watanabe-Okochi N, Kitaura J, Ono R, Harada H, Harada Y, Komeno Y, Nakajima H, Nosaka T, Inaba T, Kitamura T. Watanabe-Okochi N, et al. Blood. 2008 Apr 15;111(8):4297-308. doi: 10.1182/blood-2007-01-068346. Epub 2008 Jan 11. Blood. 2008. PMID: 18192504 Free article.
Possible involvement of RasGRP4 in leukemogenesis.
Watanabe-Okochi N, Oki T, Komeno Y, Kato N, Yuji K, Ono R, Harada Y, Harada H, Hayashi Y, Nakajima H, Nosaka T, Kitaura J, Kitamura T. Watanabe-Okochi N, et al. Int J Hematol. 2009 May;89(4):470-481. doi: 10.1007/s12185-009-0299-0. Epub 2009 Apr 7. Int J Hematol. 2009. PMID: 19350351
AID-induced T-lymphoma or B-leukemia/lymphoma in a mouse BMT model.
Komeno Y, Kitaura J, Watanabe-Okochi N, Kato N, Oki T, Nakahara F, Harada Y, Harada H, Shinkura R, Nagaoka H, Hayashi Y, Honjo T, Kitamura T. Komeno Y, et al. Leukemia. 2010 May;24(5):1018-24. doi: 10.1038/leu.2010.40. Epub 2010 Apr 1. Leukemia. 2010. PMID: 20357822
34 results