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Diarylquinolines target subunit c of mycobacterial ATP synthase.
Koul A, Dendouga N, Vergauwen K, Molenberghs B, Vranckx L, Willebrords R, Ristic Z, Lill H, Dorange I, Guillemont J, Bald D, Andries K. Koul A, et al. Nat Chem Biol. 2007 Jun;3(6):323-4. doi: 10.1038/nchembio884. Epub 2007 May 13. Nat Chem Biol. 2007. PMID: 17496888
Novel antibiotics targeting respiratory ATP synthesis in Gram-positive pathogenic bacteria.
Balemans W, Vranckx L, Lounis N, Pop O, Guillemont J, Vergauwen K, Mol S, Gilissen R, Motte M, Lançois D, De Bolle M, Bonroy K, Lill H, Andries K, Bald D, Koul A. Balemans W, et al. Among authors: koul a. Antimicrob Agents Chemother. 2012 Aug;56(8):4131-9. doi: 10.1128/AAC.00273-12. Epub 2012 May 21. Antimicrob Agents Chemother. 2012. PMID: 22615276 Free PMC article.
Essentiality of FASII pathway for Staphylococcus aureus.
Balemans W, Lounis N, Gilissen R, Guillemont J, Simmen K, Andries K, Koul A. Balemans W, et al. Among authors: koul a. Nature. 2010 Jan 21;463(7279):E3; discussion E4. doi: 10.1038/nature08667. Nature. 2010. PMID: 20090698
Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region.
McGowan DC, Balemans W, Embrechts W, Motte M, Keown JR, Buyck C, Corbera J, Funes M, Moreno L, Cooymans L, Tahri A, Eymard J, Stoops B, Strijbos R, Van den Berg J, Fodor E, Grimes JM, Koul A, Jonckers THM, Raboisson P, Guillemont J. McGowan DC, et al. Among authors: koul a. J Med Chem. 2019 Nov 14;62(21):9680-9690. doi: 10.1021/acs.jmedchem.9b01091. Epub 2019 Oct 30. J Med Chem. 2019. PMID: 31647875 Free PMC article.
335 results