Chen JC - Search Results

1

Pharmacologic inhibition of JAK-STAT signaling promotes hair growth.

Harel S, Higgins CA, Cerise JE, Dai Z, Chen JC, Clynes R, Christiano AM. Harel S, et al. Among authors: chen jc. Sci Adv. 2015 Oct 23;1(9):e1500973. doi: 10.1126/sciadv.1500973. eCollection 2015 Oct. Sci Adv. 2015. PMID: 26601320 Free PMC article.

2

Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata.

Dai Z, Chen J, Chang Y, Christiano AM. Dai Z, et al. JCI Insight. 2021 Apr 8;6(7):e142205. doi: 10.1172/jci.insight.142205. JCI Insight. 2021. PMID: 33830087 Free PMC article.

3

Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth.

Higgins CA, Chen JC, Cerise JE, Jahoda CA, Christiano AM. Higgins CA, et al. Among authors: chen jc. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19679-88. doi: 10.1073/pnas.1309970110. Epub 2013 Oct 21. Proc Natl Acad Sci U S A. 2013. PMID: 24145441 Free PMC article.

4

Master regulators of infiltrate recruitment in autoimmune disease identified through network-based molecular deconvolution.

Chen JC, Cerise JE, Jabbari A, Clynes R, Christiano AM. Chen JC, et al. Cell Syst. 2015 Nov 25;1(5):326-337. doi: 10.1016/j.cels.2015.11.001. Cell Syst. 2015. PMID: 26665180 Free PMC article.

5

Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata.

Kennedy Crispin M, Ko JM, Craiglow BG, Li S, Shankar G, Urban JR, Chen JC, Cerise JE, Jabbari A, Winge MC, Marinkovich MP, Christiano AM, Oro AE, King BA. Kennedy Crispin M, et al. Among authors: chen jc. JCI Insight. 2016 Sep 22;1(15):e89776. doi: 10.1172/jci.insight.89776. JCI Insight. 2016. PMID: 27699252 Free PMC article.

6

Out of Many, One: Computational Reconstruction of Mouse Skin using Single-Cell Transcriptomics.

Chen JC, Christiano AM. Chen JC, et al. Cell Stem Cell. 2016 Oct 6;19(4):421-422. doi: 10.1016/j.stem.2016.09.009. Cell Stem Cell. 2016. PMID: 27716520 Free article.

7

An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis.

Jabbari A, Sansaricq F, Cerise J, Chen JC, Bitterman A, Ulerio G, Borbon J, Clynes R, Christiano AM, Mackay-Wiggan J. Jabbari A, et al. Among authors: chen jc. J Invest Dermatol. 2018 Jul;138(7):1539-1545. doi: 10.1016/j.jid.2018.01.032. Epub 2018 Feb 13. J Invest Dermatol. 2018. PMID: 29452121 Free PMC article. Clinical Trial.

8

Tissue engineering of human hair follicles using a biomimetic developmental approach.

Abaci HE, Coffman A, Doucet Y, Chen J, Jacków J, Wang E, Guo Z, Shin JU, Jahoda CA, Christiano AM. Abaci HE, et al. Nat Commun. 2018 Dec 13;9(1):5301. doi: 10.1038/s41467-018-07579-y. Nat Commun. 2018. PMID: 30546011 Free PMC article.

9

Molecular signatures define alopecia areata subtypes and transcriptional biomarkers.

Jabbari A, Cerise JE, Chen JC, Mackay-Wiggan J, Duvic M, Price V, Hordinsky M, Norris D, Clynes R, Christiano AM. Jabbari A, et al. Among authors: chen jc. EBioMedicine. 2016 May;7:240-7. doi: 10.1016/j.ebiom.2016.03.036. Epub 2016 Mar 31. EBioMedicine. 2016. PMID: 27322477 Free PMC article.

10

Regulatory network analysis defines unique drug mechanisms of action and facilitates patient-drug matching in alopecia areata clinical trials.

Chen JC, Dai Z, Christiano AM. Chen JC, et al. Comput Struct Biotechnol J. 2021 Aug 19;19:4751-4758. doi: 10.1016/j.csbj.2021.08.026. eCollection 2021. Comput Struct Biotechnol J. 2021. PMID: 34504667 Free PMC article.

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