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Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.
Mansfeld J, Urban N, Priebe S, Groth M, Frahm C, Hartmann N, Gebauer J, Ravichandran M, Dommaschk A, Schmeisser S, Kuhlow D, Monajembashi S, Bremer-Streck S, Hemmerich P, Kiehntopf M, Zamboni N, Englert C, Guthke R, Kaleta C, Platzer M, Sühnel J, Witte OW, Zarse K, Ristow M. Mansfeld J, et al. Among authors: kaleta c. Nat Commun. 2015 Dec 1;6:10043. doi: 10.1038/ncomms10043. Nat Commun. 2015. PMID: 26620638 Free PMC article.
Microbiome and Metabolome Insights into the Role of the Gastrointestinal-Brain Axis in Parkinson's and Alzheimer's Disease: Unveiling Potential Therapeutic Targets.
Zacharias HU, Kaleta C, Cossais F, Schaeffer E, Berndt H, Best L, Dost T, Glüsing S, Groussin M, Poyet M, Heinzel S, Bang C, Siebert L, Demetrowitsch T, Leypoldt F, Adelung R, Bartsch T, Bosy-Westphal A, Schwarz K, Berg D. Zacharias HU, et al. Among authors: kaleta c. Metabolites. 2022 Dec 5;12(12):1222. doi: 10.3390/metabo12121222. Metabolites. 2022. PMID: 36557259 Free PMC article. Review.
Metabolic model predictions enable targeted microbiome manipulation through precision prebiotics.
Marinos G, Hamerich IK, Debray R, Obeng N, Petersen C, Taubenheim J, Zimmermann J, Blackburn D, Samuel BS, Dierking K, Franke A, Laudes M, Waschina S, Schulenburg H, Kaleta C. Marinos G, et al. Among authors: kaleta c. Microbiol Spectr. 2024 Feb 6;12(2):e0114423. doi: 10.1128/spectrum.01144-23. Epub 2024 Jan 17. Microbiol Spectr. 2024. PMID: 38230938 Free PMC article.
Evolution of E. coli in a mouse model of inflammatory bowel disease leads to a disease-specific bacterial genotype and trade-offs with clinical relevance.
Unni R, Andreani NA, Vallier M, Heinzmann SS, Taubenheim J, Guggeis MA, Tran F, Vogler O, Künzel S, Hövener JB, Rosenstiel P, Kaleta C, Dempfle A, Unterweger D, Baines JF. Unni R, et al. Among authors: kaleta c. Gut Microbes. 2023 Dec;15(2):2286675. doi: 10.1080/19490976.2023.2286675. Epub 2023 Dec 7. Gut Microbes. 2023. PMID: 38059748 Free PMC article.
Metabolic model predictions enable targeted microbiome manipulation through precision prebiotics.
Marinos G, Hamerich IK, Debray R, Obeng N, Petersen C, Taubenheim J, Zimmermann J, Blackburn D, Samuel BS, Dierking K, Franke A, Laudes M, Waschina S, Schulenburg H, Kaleta C. Marinos G, et al. Among authors: kaleta c. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.528811. doi: 10.1101/2023.02.17.528811. bioRxiv. 2023. Update in: Microbiol Spectr. 2024 Feb 6;12(2):e0114423. doi: 10.1128/spectrum.01144-23 PMID: 36824941 Free PMC article. Updated. Preprint.
In silico evidence for gluconeogenesis from fatty acids in humans.
Kaleta C, de Figueiredo LF, Werner S, Guthke R, Ristow M, Schuster S. Kaleta C, et al. PLoS Comput Biol. 2011 Jul;7(7):e1002116. doi: 10.1371/journal.pcbi.1002116. Epub 2011 Jul 21. PLoS Comput Biol. 2011. PMID: 21814506 Free PMC article.
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