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Chemical Synthesis of Ubiquitin Chains.
Hemantha HP, Bondalapati S, Singh SK, Brik A. Hemantha HP, et al. Among authors: singh sk. Curr Protoc Chem Biol. 2015 Dec 2;7(4):229-248. doi: 10.1002/9780470559277.ch150099. Curr Protoc Chem Biol. 2015. PMID: 26629614
Ubiquitin Signaling: Chemistry Comes to the Rescue.
Mali SM, Singh SK, Eid E, Brik A. Mali SM, et al. Among authors: singh sk. J Am Chem Soc. 2017 Apr 12;139(14):4971-4986. doi: 10.1021/jacs.7b00089. Epub 2017 Mar 28. J Am Chem Soc. 2017. PMID: 28328208
Diverse fate of ubiquitin chain moieties: The proximal is degraded with the target, and the distal protects the proximal from removal and recycles.
Sun H, Mali SM, Singh SK, Meledin R, Brik A, Kwon YT, Kravtsova-Ivantsiv Y, Bercovich B, Ciechanover A. Sun H, et al. Among authors: singh sk. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7805-7812. doi: 10.1073/pnas.1822148116. Epub 2019 Mar 13. Proc Natl Acad Sci U S A. 2019. PMID: 30867293 Free PMC article.
The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag.
Sahu I, Mali SM, Sulkshane P, Xu C, Rozenberg A, Morag R, Sahoo MP, Singh SK, Ding Z, Wang Y, Day S, Cong Y, Kleifeld O, Brik A, Glickman MH. Sahu I, et al. Among authors: singh sk. Nat Commun. 2021 Oct 26;12(1):6173. doi: 10.1038/s41467-021-26427-0. Nat Commun. 2021. PMID: 34702852 Free PMC article.
Dietary supplementation and the role of phytochemicals against the Alzheimer's disease: Focus on polyphenolic compounds.
Naik RA, Rajpoot R, Koiri RK, Bhardwaj R, Aldairi AF, Johargy AK, Faidah H, Babalghith AO, Hjazi A, Alsanie WF, Alamri AS, Alhomrani M, Alsharif A, Shkodina A, Singh SK. Naik RA, et al. Among authors: singh sk. J Prev Alzheimers Dis. 2025 Jan;12(1):100004. doi: 10.1016/j.tjpad.2024.100004. Epub 2025 Jan 1. J Prev Alzheimers Dis. 2025. PMID: 39800464 Free article. Review.
4,727 results