Ye N - Search Results

1

BH4 domain of Bcl-2 as a novel target for cancer therapy.

Liu Z, Wild C, Ding Y, Ye N, Chen H, Wold EA, Zhou J. Liu Z, et al. Among authors: ye n. Drug Discov Today. 2016 Jun;21(6):989-96. doi: 10.1016/j.drudis.2015.11.008. Epub 2015 Nov 26. Drug Discov Today. 2016. PMID: 26631752 Free PMC article. Review.

2

Direct Activation of Bax Protein for Cancer Therapy.

Liu Z, Ding Y, Ye N, Wild C, Chen H, Zhou J. Liu Z, et al. Among authors: ye n. Med Res Rev. 2016 Mar;36(2):313-41. doi: 10.1002/med.21379. Epub 2015 Sep 23. Med Res Rev. 2016. PMID: 26395559 Free PMC article. Review.

3

Discovery and development of natural product oridonin-inspired anticancer agents.

Ding Y, Ding C, Ye N, Liu Z, Wold EA, Chen H, Wild C, Shen Q, Zhou J. Ding Y, et al. Among authors: ye n. Eur J Med Chem. 2016 Oct 21;122:102-117. doi: 10.1016/j.ejmech.2016.06.015. Epub 2016 Jun 13. Eur J Med Chem. 2016. PMID: 27344488 Free PMC article. Review.

4

Structure-activity relationships of 2-substituted phenyl-N-phenyl-2-oxoacetohydrazonoyl cyanides as novel antagonists of exchange proteins directly activated by cAMP (EPACs).

Liu Z, Zhu Y, Chen H, Wang P, Mei FC, Ye N, Cheng X, Zhou J. Liu Z, et al. Among authors: ye n. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5163-5166. doi: 10.1016/j.bmcl.2017.10.056. Epub 2017 Oct 25. Bioorg Med Chem Lett. 2017. PMID: 29100797 Free PMC article.

5

Orphan Receptor GPR88 as an Emerging Neurotherapeutic Target.

Ye N, Li B, Mao Q, Wold EA, Tian S, Allen JA, Zhou J. Ye N, et al. ACS Chem Neurosci. 2019 Jan 16;10(1):190-200. doi: 10.1021/acschemneuro.8b00572. Epub 2018 Dec 20. ACS Chem Neurosci. 2019. PMID: 30540906 Free PMC article. Review.

6

Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases.

Ye N, Qin W, Tian S, Xu Q, Wold EA, Zhou J, Zhen XC. Ye N, et al. J Med Chem. 2020 Dec 24;63(24):15187-15217. doi: 10.1021/acs.jmedchem.0c01192. Epub 2020 Oct 28. J Med Chem. 2020. PMID: 33111525 Review.

7

Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer.

Kuang Y, Ye N, Kyani A, Ljungman M, Paulsen M, Chen H, Zhou M, Wild C, Chen H, Zhou J, Neamati N. Kuang Y, et al. Among authors: ye n. J Med Chem. 2022 Apr 28;65(8):6133-6156. doi: 10.1021/acs.jmedchem.1c02207. Epub 2022 Apr 19. J Med Chem. 2022. PMID: 35439009 Free PMC article.

8

Recent Advances in Developing K-Ras Plasma Membrane Localization Inhibitors.

Ye N, Xu Q, Li W, Wang P, Zhou J. Ye N, et al. Curr Top Med Chem. 2019;19(23):2114-2127. doi: 10.2174/1568026619666190902145116. Curr Top Med Chem. 2019. PMID: 31475899 Review.

9

Scaffold repurposing of fendiline: Identification of potent KRAS plasma membrane localization inhibitors.

Wang P, van der Hoeven D, Ye N, Chen H, Liu Z, Ma X, Montufar-Solis D, Rehl KM, Cho KJ, Thapa S, Chen W, van der Hoeven R, Frost JA, Hancock JF, Zhou J. Wang P, et al. Among authors: ye n. Eur J Med Chem. 2021 May 5;217:113381. doi: 10.1016/j.ejmech.2021.113381. Epub 2021 Mar 15. Eur J Med Chem. 2021. PMID: 33756124

10

Oridonin ring A-based diverse constructions of enone functionality: identification of novel dienone analogues effective for highly aggressive breast cancer by inducing apoptosis.

Ding C, Zhang Y, Chen H, Yang Z, Wild C, Ye N, Ester CD, Xiong A, White MA, Shen Q, Zhou J. Ding C, et al. Among authors: ye n. J Med Chem. 2013 Nov 14;56(21):8814-25. doi: 10.1021/jm401248x. Epub 2013 Oct 31. J Med Chem. 2013. PMID: 24128046 Free PMC article.

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