Zhou J - Search Results

1

BH4 domain of Bcl-2 as a novel target for cancer therapy.

Liu Z, Wild C, Ding Y, Ye N, Chen H, Wold EA, Zhou J. Liu Z, et al. Among authors: zhou j. Drug Discov Today. 2016 Jun;21(6):989-96. doi: 10.1016/j.drudis.2015.11.008. Epub 2015 Nov 26. Drug Discov Today. 2016. PMID: 26631752 Free PMC article. Review.

2

A combined bioinformatics and chemoinformatics approach for developing asymmetric bivalent AMPA receptor positive allosteric modulators as neuroprotective agents.

Chen H, Wang CZ, Ding C, Wild C, Copits B, Swanson GT, Johnson KM, Zhou J. Chen H, et al. Among authors: zhou j. ChemMedChem. 2013 Feb;8(2):226-30. doi: 10.1002/cmdc.201200554. Epub 2012 Dec 20. ChemMedChem. 2013. PMID: 23281122 Free PMC article.

3

Efficient Synthesis of ESI-09, A Novel Non-cyclic Nucleotide EPAC Antagonist.

Chen H, Ding C, Wild C, Liu H, Wang T, White MA, Cheng X, Zhou J. Chen H, et al. Among authors: zhou j. Tetrahedron Lett. 2013 Mar 20;54(12):1546-1549. doi: 10.1016/j.tetlet.2013.01.024. Tetrahedron Lett. 2013. PMID: 23459418 Free PMC article.

4

Novel nitrogen-enriched oridonin analogues with thiazole-fused A-ring: protecting group-free synthesis, enhanced anticancer profile, and improved aqueous solubility.

Ding C, Zhang Y, Chen H, Yang Z, Wild C, Chu L, Liu H, Shen Q, Zhou J. Ding C, et al. Among authors: zhou j. J Med Chem. 2013 Jun 27;56(12):5048-58. doi: 10.1021/jm400367n. Epub 2013 Jun 19. J Med Chem. 2013. PMID: 23746196 Free PMC article.

5

Overcoming synthetic challenges of oridonin A-ring structural diversification: regio- and stereoselective installation of azides and 1,2,3-triazoles at the C-1, C-2, or C-3 position.

Ding C, Zhang Y, Chen H, Wild C, Wang T, White MA, Shen Q, Zhou J. Ding C, et al. Among authors: zhou j. Org Lett. 2013 Jul 19;15(14):3718-21. doi: 10.1021/ol4015865. Epub 2013 Jul 8. Org Lett. 2013. PMID: 23834026 Free PMC article.

6

Oridonin ring A-based diverse constructions of enone functionality: identification of novel dienone analogues effective for highly aggressive breast cancer by inducing apoptosis.

Ding C, Zhang Y, Chen H, Yang Z, Wild C, Ye N, Ester CD, Xiong A, White MA, Shen Q, Zhou J. Ding C, et al. Among authors: zhou j. J Med Chem. 2013 Nov 14;56(21):8814-25. doi: 10.1021/jm401248x. Epub 2013 Oct 31. J Med Chem. 2013. PMID: 24128046 Free PMC article.

7

Recent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).

Chen H, Wild C, Zhou X, Ye N, Cheng X, Zhou J. Chen H, et al. Among authors: zhou x, zhou j. J Med Chem. 2014 May 8;57(9):3651-65. doi: 10.1021/jm401425e. Epub 2013 Nov 27. J Med Chem. 2014. PMID: 24256330 Free PMC article. Review.

8

Oridonin inhibits hepatic stellate cell proliferation and fibrogenesis.

Bohanon FJ, Wang X, Ding C, Ding Y, Radhakrishnan GL, Rastellini C, Zhou J, Radhakrishnan RS. Bohanon FJ, et al. Among authors: zhou j. J Surg Res. 2014 Jul;190(1):55-63. doi: 10.1016/j.jss.2014.03.036. Epub 2014 Mar 20. J Surg Res. 2014. PMID: 24742622 Free PMC article.

9

Transcription Factor STAT3 as a Novel Molecular Target for Cancer Prevention.

Xiong A, Yang Z, Shen Y, Zhou J, Shen Q. Xiong A, et al. Among authors: zhou j. Cancers (Basel). 2014 Apr 16;6(2):926-57. doi: 10.3390/cancers6020926. Cancers (Basel). 2014. PMID: 24743778 Free PMC article.

10

Small molecule inhibitors targeting activator protein 1 (AP-1).

Ye N, Ding Y, Wild C, Shen Q, Zhou J. Ye N, et al. Among authors: zhou j. J Med Chem. 2014 Aug 28;57(16):6930-48. doi: 10.1021/jm5004733. Epub 2014 May 27. J Med Chem. 2014. PMID: 24831826 Free PMC article.

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