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UGT1A1 genotype-dependent dose adjustment of belinostat in patients with advanced cancers using population pharmacokinetic modeling and simulation.
Peer CJ, Goey AK, Sissung TM, Erlich S, Lee MJ, Tomita Y, Trepel JB, Piekarz R, Balasubramaniam S, Bates SE, Figg WD. Peer CJ, et al. Among authors: goey ak. J Clin Pharmacol. 2016 Apr;56(4):450-60. doi: 10.1002/jcph.627. Epub 2015 Dec 4. J Clin Pharmacol. 2016. PMID: 26637161 Free PMC article. Clinical Trial.
Effects of UGT1A1 genotype on the pharmacokinetics, pharmacodynamics, and toxicities of belinostat administered by 48-hour continuous infusion in patients with cancer.
Goey AK, Sissung TM, Peer CJ, Trepel JB, Lee MJ, Tomita Y, Ehrlich S, Bryla C, Balasubramaniam S, Piekarz R, Steinberg SM, Bates SE, Figg WD. Goey AK, et al. J Clin Pharmacol. 2016 Apr;56(4):461-73. doi: 10.1002/jcph.625. Epub 2015 Nov 9. J Clin Pharmacol. 2016. PMID: 26313268 Free PMC article. Clinical Trial.
UGT genotyping in belinostat dosing.
Goey AK, Figg WD. Goey AK, et al. Pharmacol Res. 2016 Mar;105:22-7. doi: 10.1016/j.phrs.2016.01.002. Epub 2016 Jan 7. Pharmacol Res. 2016. PMID: 26773202 Free PMC article. Review.
Pharmacogenomics and histone deacetylase inhibitors.
Goey AK, Sissung TM, Peer CJ, Figg WD. Goey AK, et al. Pharmacogenomics. 2016 Nov;17(16):1807-1815. doi: 10.2217/pgs-2016-0113. Epub 2016 Oct 21. Pharmacogenomics. 2016. PMID: 27767376 Free PMC article. Review.
Sequence-Specific Pharmacokinetic and Pharmacodynamic Phase I/Ib Study of Olaparib Tablets and Carboplatin in Women's Cancer.
Lee JM, Peer CJ, Yu M, Amable L, Gordon N, Annunziata CM, Houston N, Goey AK, Sissung TM, Parker B, Minasian L, Chiou VL, Murphy RF, Widemann BC, Figg WD, Kohn EC. Lee JM, et al. Among authors: goey ak. Clin Cancer Res. 2017 Mar 15;23(6):1397-1406. doi: 10.1158/1078-0432.CCR-16-1546. Epub 2016 Sep 23. Clin Cancer Res. 2017. PMID: 27663600 Free PMC article. Clinical Trial.
Structural Elucidation and Synthesis of Eudistidine A: An Unusual Polycyclic Marine Alkaloid that Blocks Interaction of the Protein Binding Domains of p300 and HIF-1α.
Chan ST, Patel PR, Ransom TR, Henrich CJ, McKee TC, Goey AK, Cook KM, Figg WD, McMahon JB, Schnermann MJ, Gustafson KR. Chan ST, et al. Among authors: goey ak. J Am Chem Soc. 2015 Apr 29;137(16):5569-75. doi: 10.1021/jacs.5b02156. Epub 2015 Apr 20. J Am Chem Soc. 2015. PMID: 25892103 Free PMC article.
35 results