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Page 1
Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials?
Terzić N, Konstantinović J, Tot M, Burojević J, Djurković-Djaković O, Srbljanović J, Štajner T, Verbić T, Zlatović M, Machado M, Albuquerque IS, Prudêncio M, Sciotti RJ, Pecic S, D'Alessandro S, Taramelli D, Šolaja BA. Terzić N, et al. Among authors: konstantinovic j. J Med Chem. 2016 Jan 14;59(1):264-81. doi: 10.1021/acs.jmedchem.5b01374. Epub 2015 Dec 18. J Med Chem. 2016. PMID: 26640981
Second generation steroidal 4-aminoquinolines are potent, dual-target inhibitors of the botulinum neurotoxin serotype A metalloprotease and P. falciparum malaria.
Videnović M, Opsenica DM, Burnett JC, Gomba L, Nuss JE, Selaković Z, Konstantinović J, Krstić M, Segan S, Zlatović M, Sciotti RJ, Bavari S, Solaja BA. Videnović M, et al. Among authors: konstantinovic j. J Med Chem. 2014 May 22;57(10):4134-53. doi: 10.1021/jm500033r. Epub 2014 May 1. J Med Chem. 2014. PMID: 24742203 Free PMC article.
Antimalarials with Benzothiophene Moieties as Aminoquinoline Partners.
Konstantinović J, Videnović M, Srbljanović J, Djurković-Djaković O, Bogojević K, Sciotti R, Šolaja B. Konstantinović J, et al. Molecules. 2017 Feb 24;22(3):343. doi: 10.3390/molecules22030343. Molecules. 2017. PMID: 28245583 Free PMC article.
Examination of the antimalarial potential of experimental aminoquinolines: poor in vitro effect does not preclude in vivo efficacy.
Srbljanović J, Štajner T, Konstantinović J, Terzić-Jovanović N, Uzelac A, Bobić B, Šolaja BA, Djurković-Djaković O. Srbljanović J, et al. Among authors: konstantinovic j. Int J Antimicrob Agents. 2017 Sep;50(3):461-466. doi: 10.1016/j.ijantimicag.2017.06.002. Epub 2017 Jun 28. Int J Antimicrob Agents. 2017. PMID: 28668677
New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model.
Konstantinović J, Kiris E, Kota KP, Kugelman-Tonos J, Videnović M, Cazares LH, Terzić Jovanović N, Verbić TŽ, Andjelković B, Duplantier AJ, Bavari S, Šolaja BA. Konstantinović J, et al. J Med Chem. 2018 Feb 22;61(4):1595-1608. doi: 10.1021/acs.jmedchem.7b01710. Epub 2018 Feb 6. J Med Chem. 2018. PMID: 29385334 Free PMC article.
Human serum albumin binding of certain antimalarials.
Marković OS, Cvijetić IN, Zlatović MV, Opsenica IM, Konstantinović JM, Terzić Jovanović NV, Šolaja BA, Verbić TŽ. Marković OS, et al. Among authors: konstantinovic jm. Spectrochim Acta A Mol Biomol Spectrosc. 2018 Mar 5;192:128-139. doi: 10.1016/j.saa.2017.10.061. Epub 2017 Nov 9. Spectrochim Acta A Mol Biomol Spectrosc. 2018. PMID: 29128746
N-Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases.
Konstantinović J, Yahiaoui S, Alhayek A, Haupenthal J, Schönauer E, Andreas A, Kany AM, Müller R, Koehnke J, Berger FK, Bischoff M, Hartmann RW, Brandstetter H, Hirsch AKH. Konstantinović J, et al. J Med Chem. 2020 Aug 13;63(15):8359-8368. doi: 10.1021/acs.jmedchem.0c00584. Epub 2020 Jun 17. J Med Chem. 2020. PMID: 32470298 Free PMC article.
N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases.
Kaya C, Konstantinović J, Kany AM, Andreas A, Kramer JS, Brunst S, Weizel L, Rotter MJ, Frank D, Yahiaoui S, Müller R, Hartmann RW, Haupenthal J, Proschak E, Wichelhaus TA, Hirsch AKH. Kaya C, et al. Among authors: konstantinovic j. J Med Chem. 2022 Mar 10;65(5):3913-3922. doi: 10.1021/acs.jmedchem.1c01755. Epub 2022 Feb 21. J Med Chem. 2022. PMID: 35188771
16 results