La Spada AR - Search Results

1

PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically.

Dickey AS, Pineda VV, Tsunemi T, Liu PP, Miranda HC, Gilmore-Hall SK, Lomas N, Sampat KR, Buttgereit A, Torres MJ, Flores AL, Arreola M, Arbez N, Akimov SS, Gaasterland T, Lazarowski ER, Ross CA, Yeo GW, Sopher BL, Magnuson GK, Pinkerton AB, Masliah E, La Spada AR. Dickey AS, et al. Among authors: la spada ar. Nat Med. 2016 Jan;22(1):37-45. doi: 10.1038/nm.4003. Epub 2015 Dec 7. Nat Med. 2016. PMID: 26642438 Free PMC article.

2

In vivo expansion of trinucleotide repeats yields plasmid and YAC constructs for targeting and transgenesis.

Sopher BL, Myrick SB, Hong JY, Smith AC, La Spada AR. Sopher BL, et al. Among authors: la spada ar. Gene. 2000 Dec 31;261(2):383-90. doi: 10.1016/s0378-1119(00)00508-4. Gene. 2000. PMID: 11167027

3

Genomic organization, chromosome location, and expression analysis of mouse beta-synuclein, a candidate for involvement in neurodegeneration.

Sopher BL, Koszdin KL, McClain ME, Myrick SB, Martinez RA, Smith AC, La Spada AR. Sopher BL, et al. Among authors: la spada ar. Cytogenet Cell Genet. 2001;93(1-2):117-23. doi: 10.1159/000056962. Cytogenet Cell Genet. 2001. PMID: 11474193

4

Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7.

La Spada AR, Fu YH, Sopher BL, Libby RT, Wang X, Li LY, Einum DD, Huang J, Possin DE, Smith AC, Martinez RA, Koszdin KL, Treuting PM, Ware CB, Hurley JB, Ptácek LJ, Chen S. La Spada AR, et al. Neuron. 2001 Sep 27;31(6):913-27. doi: 10.1016/s0896-6273(01)00422-6. Neuron. 2001. PMID: 11580893 Free article.

5

Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.

Garden GA, Libby RT, Fu YH, Kinoshita Y, Huang J, Possin DE, Smith AC, Martinez RA, Fine GC, Grote SK, Ware CB, Einum DD, Morrison RS, Ptacek LJ, Sopher BL, La Spada AR. Garden GA, et al. Among authors: la spada ar. J Neurosci. 2002 Jun 15;22(12):4897-905. doi: 10.1523/JNEUROSCI.22-12-04897.2002. J Neurosci. 2002. PMID: 12077187 Free PMC article.

6

Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects.

Luthi-Carter R, Strand AD, Hanson SA, Kooperberg C, Schilling G, La Spada AR, Merry DE, Young AB, Ross CA, Borchelt DR, Olson JM. Luthi-Carter R, et al. Among authors: la spada ar. Hum Mol Genet. 2002 Aug 15;11(17):1927-37. doi: 10.1093/hmg/11.17.1927. Hum Mol Genet. 2002. PMID: 12165555

7

Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization.

Chen S, Peng GH, Wang X, Smith AC, Grote SK, Sopher BL, La Spada AR. Chen S, et al. Among authors: la spada ar. Hum Mol Genet. 2004 Jan 1;13(1):53-67. doi: 10.1093/hmg/ddh005. Epub 2003 Nov 12. Hum Mol Genet. 2004. PMID: 14613968

8

Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration.

Sopher BL, Thomas PS Jr, LaFevre-Bernt MA, Holm IE, Wilke SA, Ware CB, Jin LW, Libby RT, Ellerby LM, La Spada AR. Sopher BL, et al. Among authors: la spada ar. Neuron. 2004 Mar 4;41(5):687-99. doi: 10.1016/s0896-6273(04)00082-0. Neuron. 2004. PMID: 15003169 Free article.

9

The power of the dark side: Huntington's disease protein and p53 form a deadly alliance.

La Spada AR, Morrison RS. La Spada AR, et al. Neuron. 2005 Jul 7;47(1):1-3. doi: 10.1016/j.neuron.2005.06.023. Neuron. 2005. PMID: 15996541 Free article.

10

The Purkinje cell degeneration 5J mutation is a single amino acid insertion that destabilizes Nna1 protein.

Chakrabarti L, Neal JT, Miles M, Martinez RA, Smith AC, Sopher BL, La Spada AR. Chakrabarti L, et al. Among authors: la spada ar. Mamm Genome. 2006 Feb;17(2):103-10. doi: 10.1007/s00335-005-0096-x. Epub 2006 Feb 7. Mamm Genome. 2006. PMID: 16465590

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

178 results

Search Page

Filters