Xu Z - Search Results

1

Design, synthesis, and evaluation of potent Wnt signaling inhibitors featuring a fused 3-ring system.

Xu Z, Li J, Wu Y, Sun Z, Luo L, Hu Z, He S, Zheng J, Zhang H, Zhang X. Xu Z, et al. Eur J Med Chem. 2016 Jan 27;108:154-165. doi: 10.1016/j.ejmech.2015.11.026. Epub 2015 Nov 22. Eur J Med Chem. 2016. PMID: 26647303

2

Exploration of the linkage elements of porcupine antagonists led to potent Wnt signaling pathway inhibitors.

Dong Y, Li K, Xu Z, Ma H, Zheng J, Hu Z, He S, Wu Y, Sun Z, Luo L, Li J, Zhang H, Zhang X. Dong Y, et al. Among authors: xu z. Bioorg Med Chem. 2015 Nov 1;23(21):6855-68. doi: 10.1016/j.bmc.2015.09.048. Epub 2015 Oct 1. Bioorg Med Chem. 2015. PMID: 26455655

3

Design, synthesis, and evaluation of novel porcupine inhibitors featuring a fused 3-ring system based on the 'reversed' amide scaffold.

Xu Z, Xu X, O'Laoi R, Ma H, Zheng J, Chen S, Luo L, Hu Z, He S, Li J, Zhang H, Zhang X. Xu Z, et al. Among authors: xu x. Bioorg Med Chem. 2016 Nov 15;24(22):5861-5872. doi: 10.1016/j.bmc.2016.09.041. Epub 2016 Sep 17. Bioorg Med Chem. 2016. PMID: 27692509

4

Design, synthesis and evaluation of a series of non-steroidal anti-inflammatory drug conjugates as novel neuroinflammatory inhibitors.

Xu Z, Wu J, Zheng J, Ma H, Zhang H, Zhen X, Zheng LT, Zhang X. Xu Z, et al. Int Immunopharmacol. 2015 Apr;25(2):528-37. doi: 10.1016/j.intimp.2015.02.033. Epub 2015 Mar 10. Int Immunopharmacol. 2015. PMID: 25765352

5

Reaction intermediate analogues as bisubstrate inhibitors of pantothenate synthetase.

Xu Z, Yin W, Martinelli LK, Evans J, Chen J, Yu Y, Wilson DJ, Mizrahi V, Qiao C, Aldrich CC. Xu Z, et al. Bioorg Med Chem. 2014 Mar 1;22(5):1726-35. doi: 10.1016/j.bmc.2014.01.017. Epub 2014 Jan 23. Bioorg Med Chem. 2014. PMID: 24507827 Free PMC article.

6

Synthesis of biotinylated-LPG as a chemical biology tool enabling discovery of ALCAT1 modulators.

Huang H, Zhou R, Wen H, Xu Z, Zhang S, Wang W, Krosky D, Miller R. Huang H, et al. Among authors: xu z. Bioorg Med Chem Lett. 2022 Sep 15;72:128861. doi: 10.1016/j.bmcl.2022.128861. Epub 2022 Jun 16. Bioorg Med Chem Lett. 2022. PMID: 35718103

7

Enhancing drug solubility through competitive adsorption on silica nanosurfaces with ultrahigh silanol densities.

Xu Z, Zhu C, Shen H, Liu Y, Tang J, Weitz DA, Xu L. Xu Z, et al. Proc Natl Acad Sci U S A. 2025 Jan 28;122(4):e2423426122. doi: 10.1073/pnas.2423426122. Epub 2025 Jan 23. Proc Natl Acad Sci U S A. 2025. PMID: 39847323

8

Molecular mechanism of ligand recognition and activation of lysophosphatidic acid receptor LPAR6.

Duan Y, Xu Z, Hao B, Zhang A, Guo C, He Y. Duan Y, et al. Among authors: xu z. Proc Natl Acad Sci U S A. 2025 Jan 28;122(4):e2415426122. doi: 10.1073/pnas.2415426122. Epub 2025 Jan 23. Proc Natl Acad Sci U S A. 2025. PMID: 39847322

9

A Stereoselective Oxidative Dimerization En Route to (-)-Lomaiviticin A.

DiBello M, Xu Z, Palazzo AM, Herzon SB. DiBello M, et al. Among authors: xu z. Org Lett. 2025 Jan 23. doi: 10.1021/acs.orglett.4c04098. Online ahead of print. Org Lett. 2025. PMID: 39846772

10

Impact of Acute Myocardial Injury on Short- and Long-Term Outcomes in Patients With Primary Intracerebral Hemorrhage.

Ma S, Li J, Kong Q, Xu Z, Wu H, Jin Y, Ye X, Luo D, Tong L, Gao F. Ma S, et al. Among authors: xu z. J Am Heart Assoc. 2025 Jan 23:e037053. doi: 10.1161/JAHA.124.037053. Online ahead of print. J Am Heart Assoc. 2025. PMID: 39846256

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