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Transplantation of hESC-derived hepatocytes protects mice from liver injury.
Tolosa L, Caron J, Hannoun Z, Antoni M, López S, Burks D, Castell JV, Weber A, Gomez-Lechon MJ, Dubart-Kupperschmitt A. Tolosa L, et al. Among authors: hannoun z. Stem Cell Res Ther. 2015 Dec 12;6:246. doi: 10.1186/s13287-015-0227-6. Stem Cell Res Ther. 2015. PMID: 26652177 Free PMC article.
An atypical human induced pluripotent stem cell line with a complex, stable, and balanced genomic rearrangement including a large de novo 1q uniparental disomy.
Steichen C, Maluenda J, Tosca L, Luce E, Pineau D, Dianat N, Hannoun Z, Tachdjian G, Melki J, Dubart-Kupperschmitt A. Steichen C, et al. Among authors: hannoun z. Stem Cells Transl Med. 2015 Mar;4(3):224-9. doi: 10.5966/sctm.2014-0186. Epub 2015 Feb 3. Stem Cells Transl Med. 2015. PMID: 25650439 Free PMC article.
Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism.
Hay DC, Pernagallo S, Diaz-Mochon JJ, Medine CN, Greenhough S, Hannoun Z, Schrader J, Black JR, Fletcher J, Dalgetty D, Thompson AI, Newsome PN, Forbes SJ, Ross JA, Bradley M, Iredale JP. Hay DC, et al. Among authors: hannoun z. Stem Cell Res. 2011 Mar;6(2):92-102. doi: 10.1016/j.scr.2010.12.002. Epub 2010 Dec 10. Stem Cell Res. 2011. PMID: 21277274 Free article.
SUMOylation of HNF4α regulates protein stability and hepatocyte function.
Zhou W, Hannoun Z, Jaffray E, Medine CN, Black JR, Greenhough S, Zhu L, Ross JA, Forbes S, Wilmut I, Iredale JP, Hay RT, Hay DC. Zhou W, et al. Among authors: hannoun z. J Cell Sci. 2012 Aug 1;125(Pt 15):3630-5. doi: 10.1242/jcs.102889. Epub 2012 Apr 14. J Cell Sci. 2012. PMID: 22505616 Free PMC article.
Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling.
Hay DC, Fletcher J, Payne C, Terrace JD, Gallagher RC, Snoeys J, Black JR, Wojtacha D, Samuel K, Hannoun Z, Pryde A, Filippi C, Currie IS, Forbes SJ, Ross JA, Newsome PN, Iredale JP. Hay DC, et al. Among authors: hannoun z. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12301-6. doi: 10.1073/pnas.0806522105. Epub 2008 Aug 21. Proc Natl Acad Sci U S A. 2008. PMID: 18719101 Free PMC article.
30 results