Iyer A - Search Results

1

Differential Anti-inflammatory Activity of HDAC Inhibitors in Human Macrophages and Rat Arthritis.

Lohman RJ, Iyer A, Fairlie TJ, Cotterell A, Gupta P, Reid RC, Vesey DA, Sweet MJ, Fairlie DP. Lohman RJ, et al. Among authors: iyer a. J Pharmacol Exp Ther. 2016 Feb;356(2):387-96. doi: 10.1124/jpet.115.229328. Epub 2015 Dec 10. J Pharmacol Exp Ther. 2016. PMID: 26660228

2

Inflammatory lipid mediators in adipocyte function and obesity.

Iyer A, Fairlie DP, Prins JB, Hammock BD, Brown L. Iyer A, et al. Nat Rev Endocrinol. 2010 Feb;6(2):71-82. doi: 10.1038/nrendo.2009.264. Nat Rev Endocrinol. 2010. PMID: 20098448 Review.

3

Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats.

Iyer A, Fenning A, Lim J, Le GT, Reid RC, Halili MA, Fairlie DP, Brown L. Iyer A, et al. Br J Pharmacol. 2010 Apr;159(7):1408-17. doi: 10.1111/j.1476-5381.2010.00637.x. Epub 2010 Feb 24. Br J Pharmacol. 2010. PMID: 20180942 Free PMC article.

4

Inhibition of inflammation and fibrosis by a complement C5a receptor antagonist in DOCA-salt hypertensive rats.

Iyer A, Woodruff TM, Wu MC, Stylianou C, Reid RC, Fairlie DP, Taylor SM, Brown L. Iyer A, et al. J Cardiovasc Pharmacol. 2011 Nov;58(5):479-86. doi: 10.1097/FJC.0b013e31822a7a09. J Cardiovasc Pharmacol. 2011. PMID: 21753735

5

Lysine acetylation in obesity, diabetes and metabolic disease.

Iyer A, Fairlie DP, Brown L. Iyer A, et al. Immunol Cell Biol. 2012 Jan;90(1):39-46. doi: 10.1038/icb.2011.99. Epub 2011 Nov 15. Immunol Cell Biol. 2012. PMID: 22083525 Review.

6

Towards isozyme-selective HDAC inhibitors for interrogating disease.

Gupta P, Reid RC, Iyer A, Sweet MJ, Fairlie DP. Gupta P, et al. Among authors: iyer a. Curr Top Med Chem. 2012;12(14):1479-99. doi: 10.2174/156802612802652420. Curr Top Med Chem. 2012. PMID: 22827519 Review.

7

An inhibitor of phospholipase A2 group IIA modulates adipocyte signaling and protects against diet-induced metabolic syndrome in rats.

Iyer A, Lim J, Poudyal H, Reid RC, Suen JY, Webster J, Prins JB, Whitehead JP, Fairlie DP, Brown L. Iyer A, et al. Diabetes. 2012 Sep;61(9):2320-9. doi: 10.2337/db11-1179. Diabetes. 2012. PMID: 22923652 Free PMC article.

8

C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling.

Lim J, Iyer A, Suen JY, Seow V, Reid RC, Brown L, Fairlie DP. Lim J, et al. Among authors: iyer a. FASEB J. 2013 Feb;27(2):822-31. doi: 10.1096/fj.12-220582. Epub 2012 Nov 1. FASEB J. 2013. PMID: 23118029

9

Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages.

Shakespear MR, Hohenhaus DM, Kelly GM, Kamal NA, Gupta P, Labzin LI, Schroder K, Garceau V, Barbero S, Iyer A, Hume DA, Reid RC, Irvine KM, Fairlie DP, Sweet MJ. Shakespear MR, et al. Among authors: iyer a. J Biol Chem. 2013 Aug 30;288(35):25362-25374. doi: 10.1074/jbc.M113.496281. Epub 2013 Jul 12. J Biol Chem. 2013. PMID: 23853092 Free PMC article.

10

An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation.

Hohenhaus DM, Schaale K, Le Cao KA, Seow V, Iyer A, Fairlie DP, Sweet MJ. Hohenhaus DM, et al. Among authors: iyer a. Immunobiology. 2013 Nov;218(11):1345-53. doi: 10.1016/j.imbio.2013.07.001. Epub 2013 Jul 15. Immunobiology. 2013. PMID: 23948647

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