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Pyrrolocin A, a 3-Decalinoyltetramic Acid with Selective Biological Activity, Isolated from Amazonian Cultures of the Novel Endophyte Diaporthales sp. E6927E.
Patridge EV, Darnell A, Kucera K, Phillips GM, Bokesch HR, Gustafson KR, Spakowicz DJ, Zhou L, Hungerford WM, Plummer M, Hoyer D, Narváez-Trujillo A, Phillips AJ, Strobel SA. Patridge EV, et al. Among authors: hoyer d. Nat Prod Commun. 2015 Oct;10(10):1649-54. Nat Prod Commun. 2015. PMID: 26669095 Free PMC article.
Target selection for FDA-approved medicines.
Kinch MS, Hoyer D, Patridge E, Plummer M. Kinch MS, et al. Among authors: hoyer d. Drug Discov Today. 2015 Jul;20(7):784-9. doi: 10.1016/j.drudis.2014.11.001. Epub 2014 Nov 11. Drug Discov Today. 2015. PMID: 25462532 Review.
A γ-lactam siderophore antibiotic effective against multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter spp.
Goldberg JA, Kumar V, Spencer EJ, Hoyer D, Marshall SH, Hujer AM, Hujer KM, Bethel CR, Papp-Wallace KM, Perez F, Jacobs MR, van Duin D, Kreiswirth BN, van den Akker F, Plummer MS, Bonomo RA. Goldberg JA, et al. Among authors: hoyer d. Eur J Med Chem. 2021 Aug 5;220:113436. doi: 10.1016/j.ejmech.2021.113436. Epub 2021 Apr 8. Eur J Med Chem. 2021. PMID: 33933754 Free PMC article.
A γ-Lactam Siderophore Antibiotic Effective against Multidrug-Resistant Gram-Negative Bacilli.
Goldberg JA, Nguyen H, Kumar V, Spencer EJ, Hoyer D, Marshall EK, Cmolik A, O'Shea M, Marshall SH, Hujer AM, Hujer KM, Rudin SD, Domitrovic TN, Bethel CR, Papp-Wallace KM, Logan LK, Perez F, Jacobs MR, van Duin D, Kreiswirth BM, Bonomo RA, Plummer MS, van den Akker F. Goldberg JA, et al. Among authors: hoyer d. J Med Chem. 2020 Jun 11;63(11):5990-6002. doi: 10.1021/acs.jmedchem.0c00255. Epub 2020 Jun 2. J Med Chem. 2020. PMID: 32420736 Free PMC article.
YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors.
Stachelek GC, Peterson-Roth E, Liu Y, Fernandez RJ 3rd, Pike LR, Qian JM, Abriola L, Hoyer D, Hungerford W, Merkel J, Glazer PM. Stachelek GC, et al. Among authors: hoyer d. Mol Cancer Res. 2015 Oct;13(10):1389-97. doi: 10.1158/1541-7786.MCR-15-0036. Epub 2015 Jun 26. Mol Cancer Res. 2015. PMID: 26116172 Free PMC article.
566 results