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5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.
Hopkinson RJ, Tumber A, Yapp C, Chowdhury R, Aik W, Che KH, Li XS, Kristensen JBL, King ONF, Chan MC, Yeoh KK, Choi H, Walport LJ, Thinnes CC, Bush JT, Lejeune C, Rydzik AM, Rose NR, Bagg EA, McDonough MA, Krojer T, Yue WW, Ng SS, Olsen L, Brennan PE, Oppermann U, Muller-Knapp S, Klose RJ, Ratcliffe PJ, Schofield CJ, Kawamura A. Hopkinson RJ, et al. Among authors: bush jt. Chem Sci. 2013 Aug 1;4(8):3110-3117. doi: 10.1039/C3SC51122G. Chem Sci. 2013. PMID: 26682036 Free PMC article.
A cell-permeable ester derivative of the JmjC histone demethylase inhibitor IOX1.
Schiller R, Scozzafava G, Tumber A, Wickens JR, Bush JT, Rai G, Lejeune C, Choi H, Yeh TL, Chan MC, Mott BT, McCullagh JS, Maloney DJ, Schofield CJ, Kawamura A. Schiller R, et al. Among authors: bush jt. ChemMedChem. 2014 Mar;9(3):566-71. doi: 10.1002/cmdc.201300428. Epub 2014 Feb 6. ChemMedChem. 2014. PMID: 24504543 Free PMC article.
YcfDRM is a thermophilic oxygen-dependent ribosomal protein uL16 oxygenase.
Sekirnik R, Wilkins SE, Bush J, Tarhonskaya H, Münzel M, Hussein A, Flashman E, Mohammed S, McDonough MA, Loenarz C, Schofield CJ. Sekirnik R, et al. Extremophiles. 2018 May;22(3):553-562. doi: 10.1007/s00792-018-1016-9. Epub 2018 Mar 9. Extremophiles. 2018. PMID: 29523972 Free PMC article.
Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation.
Thomas AM, Serafini M, Grant EK, Coombs EAJ, Bluck JP, Schiedel M, McDonough MA, Reynolds JK, Lee B, Platt M, Sharlandjieva V, Biggin PC, Duarte F, Milne TA, Bush JT, Conway SJ. Thomas AM, et al. Among authors: bush jt. ACS Chem Biol. 2023 Nov 17;18(11):2405-2417. doi: 10.1021/acschembio.3c00437. Epub 2023 Oct 24. ACS Chem Biol. 2023. PMID: 37874862 Free PMC article.
One-Step Synthesis of Photoaffinity Probes for Live-Cell MS-Based Proteomics.
Fallon DJ, Lehmann S, Chung CW, Phillipou A, Eberl C, Fantom KGM, Zappacosta F, Patel VK, Bantscheff M, Schofield CJ, Tomkinson NCO, Bush JT. Fallon DJ, et al. Among authors: bush jt. Chemistry. 2021 Dec 20;27(71):17880-17888. doi: 10.1002/chem.202102036. Epub 2021 Sep 14. Chemistry. 2021. PMID: 34328642 Free article.
32 results