Clements DR - Search Results

1

Dendritic Cells in Oncolytic Virus-Based Anti-Cancer Therapy.

Kim Y, Clements DR, Sterea AM, Jang HW, Gujar SA, Lee PW. Kim Y, et al. Among authors: clements dr. Viruses. 2015 Dec 9;7(12):6506-25. doi: 10.3390/v7122953. Viruses. 2015. PMID: 26690204 Free PMC article. Review.

2

Multifaceted therapeutic targeting of ovarian peritoneal carcinomatosis through virus-induced immunomodulation.

Gujar S, Dielschneider R, Clements D, Helson E, Shmulevitz M, Marcato P, Pan D, Pan LZ, Ahn DG, Alawadhi A, Lee PW. Gujar S, et al. Mol Ther. 2013 Feb;21(2):338-47. doi: 10.1038/mt.2012.228. Epub 2012 Nov 13. Mol Ther. 2013. PMID: 23299799 Free PMC article.

3

Gemcitabine-mediated tumour regression and p53-dependent gene expression: implications for colon and pancreatic cancer therapy.

Hill R, Rabb M, Madureira PA, Clements D, Gujar SA, Waisman DM, Giacomantonio CA, Lee PW. Hill R, et al. Cell Death Dis. 2013 Sep 5;4(9):e791. doi: 10.1038/cddis.2013.307. Cell Death Dis. 2013. PMID: 24008735 Free PMC article.

4

Gemcitabine enhances the efficacy of reovirus-based oncotherapy through anti-tumour immunological mechanisms.

Gujar SA, Clements D, Dielschneider R, Helson E, Marcato P, Lee PW. Gujar SA, et al. Br J Cancer. 2014 Jan 7;110(1):83-93. doi: 10.1038/bjc.2013.695. Epub 2013 Nov 26. Br J Cancer. 2014. PMID: 24281006 Free PMC article.

5

The NAD+ synthesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT-2) is a p53 downstream target.

Pan LZ, Ahn DG, Sharif T, Clements D, Gujar SA, Lee PW. Pan LZ, et al. Cell Cycle. 2014;13(6):1041-8. doi: 10.4161/cc.28128. Epub 2014 Feb 7. Cell Cycle. 2014. PMID: 24552824 Free PMC article.

6

Two is better than one: Complementing oncolytic virotherapy with gemcitabine to potentiate antitumor immune responses.

Gujar SA, Clements D, Lee PW. Gujar SA, et al. Oncoimmunology. 2014 Jan 1;3(1):e27622. doi: 10.4161/onci.27622. Epub 2014 Jan 6. Oncoimmunology. 2014. PMID: 24804161 Free PMC article.

7

Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling.

Marcato P, Dean CA, Liu RZ, Coyle KM, Bydoun M, Wallace M, Clements D, Turner C, Mathenge EG, Gujar SA, Giacomantonio CA, Mackey JR, Godbout R, Lee PW. Marcato P, et al. Mol Oncol. 2015 Jan;9(1):17-31. doi: 10.1016/j.molonc.2014.07.010. Epub 2014 Jul 24. Mol Oncol. 2015. PMID: 25106087 Free PMC article. Clinical Trial.

8

Core needle biopsy of breast cancer tumors increases distant metastases in a mouse model.

Mathenge EG, Dean CA, Clements D, Vaghar-Kashani A, Photopoulos S, Coyle KM, Giacomantonio M, Malueth B, Nunokawa A, Jordan J, Lewis JD, Gujar SA, Marcato P, Lee PW, Giacomantonio CA. Mathenge EG, et al. Neoplasia. 2014 Nov 20;16(11):950-60. doi: 10.1016/j.neo.2014.09.004. eCollection 2014 Nov. Neoplasia. 2014. PMID: 25425969 Free PMC article.

9

Newly recruited CD11b+, GR-1+, Ly6C(high) myeloid cells augment tumor-associated immunosuppression immediately following the therapeutic administration of oncolytic reovirus.

Clements DR, Sterea AM, Kim Y, Helson E, Dean CA, Nunokawa A, Coyle KM, Sharif T, Marcato P, Gujar SA, Lee PW. Clements DR, et al. J Immunol. 2015 May 1;194(9):4397-412. doi: 10.4049/jimmunol.1402132. Epub 2015 Mar 30. J Immunol. 2015. PMID: 25825443

10

The NAD(+) salvage pathway modulates cancer cell viability via p73.

Sharif T, Ahn DG, Liu RZ, Pringle E, Martell E, Dai C, Nunokawa A, Kwak M, Clements D, Murphy JP, Dean C, Marcato P, McCormick C, Godbout R, Gujar SA, Lee PW. Sharif T, et al. Cell Death Differ. 2016 Apr;23(4):669-80. doi: 10.1038/cdd.2015.134. Epub 2015 Nov 20. Cell Death Differ. 2016. PMID: 26586573 Free PMC article.

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