Gao Y - Search Results

1

Genetic disruption of Ano5 in mice does not recapitulate human ANO5-deficient muscular dystrophy.

Xu J, El Refaey M, Xu L, Zhao L, Gao Y, Floyd K, Karaze T, Janssen PM, Han R. Xu J, et al. Among authors: gao y. Skelet Muscle. 2015 Dec 21;5:43. doi: 10.1186/s13395-015-0069-z. eCollection 2015. Skelet Muscle. 2015. PMID: 26693275 Free PMC article.

2

CRISPR-mediated Genome Editing Restores Dystrophin Expression and Function in mdx Mice.

Xu L, Park KH, Zhao L, Xu J, El Refaey M, Gao Y, Zhu H, Ma J, Han R. Xu L, et al. Among authors: gao y. Mol Ther. 2016 Mar;24(3):564-9. doi: 10.1038/mt.2015.192. Epub 2015 Oct 9. Mol Ther. 2016. PMID: 26449883 Free PMC article.

3

Empower multiplex cell and tissue-specific CRISPR-mediated gene manipulation with self-cleaving ribozymes and tRNA.

Xu L, Zhao L, Gao Y, Xu J, Han R. Xu L, et al. Among authors: gao y. Nucleic Acids Res. 2017 Mar 17;45(5):e28. doi: 10.1093/nar/gkw1048. Nucleic Acids Res. 2017. PMID: 27799472 Free PMC article.

4

In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.

El Refaey M, Xu L, Gao Y, Canan BD, Adesanya TMA, Warner SC, Akagi K, Symer DE, Mohler PJ, Ma J, Janssen PML, Han R. El Refaey M, et al. Among authors: gao y. Circ Res. 2017 Sep 29;121(8):923-929. doi: 10.1161/CIRCRESAHA.117.310996. Epub 2017 Aug 8. Circ Res. 2017. PMID: 28790199 Free PMC article.

5

A novel ANO5 splicing variant in a LGMD2L patient leads to production of a truncated aggregation-prone Ano5 peptide.

Xu J, Xu L, Lau YS, Gao Y, Moore SA, Han R. Xu J, et al. Among authors: gao y. J Pathol Clin Res. 2018 Apr;4(2):135-145. doi: 10.1002/cjp2.92. Epub 2018 Mar 1. J Pathol Clin Res. 2018. PMID: 29665321 Free PMC article.

6

Development of muscular dystrophy in a CRISPR-engineered mutant rabbit model with frame-disrupting ANO5 mutations.

Sui T, Xu L, Lau YS, Liu D, Liu T, Gao Y, Lai L, Han R, Li Z. Sui T, et al. Among authors: gao y. Cell Death Dis. 2018 May 22;9(6):609. doi: 10.1038/s41419-018-0674-y. Cell Death Dis. 2018. PMID: 29789544 Free PMC article.

7

A novel rabbit model of Duchenne muscular dystrophy generated by CRISPR/Cas9.

Sui T, Lau YS, Liu D, Liu T, Xu L, Gao Y, Lai L, Li Z, Han R. Sui T, et al. Among authors: gao y. Dis Model Mech. 2018 Jun 4;11(6):dmm032201. doi: 10.1242/dmm.032201. Dis Model Mech. 2018. PMID: 29871865 Free PMC article.

8

Adeno-Associated Virus-Mediated Delivery of CRISPR for Cardiac Gene Editing in Mice.

Xu L, Gao Y, Lau YS, Han R. Xu L, et al. Among authors: gao y. J Vis Exp. 2018 Aug 2;(138):57560. doi: 10.3791/57560. J Vis Exp. 2018. PMID: 30124643 Free PMC article.

9

Automated muscle histopathology analysis using CellProfiler.

Lau YS, Xu L, Gao Y, Han R. Lau YS, et al. Among authors: gao y. Skelet Muscle. 2018 Oct 18;8(1):32. doi: 10.1186/s13395-018-0178-6. Skelet Muscle. 2018. PMID: 30336774 Free PMC article.

10

Life-Long AAV-Mediated CRISPR Genome Editing in Dystrophic Heart Improves Cardiomyopathy without Causing Serious Lesions in mdx Mice.

Xu L, Lau YS, Gao Y, Li H, Han R. Xu L, et al. Among authors: gao y. Mol Ther. 2019 Aug 7;27(8):1407-1414. doi: 10.1016/j.ymthe.2019.05.001. Epub 2019 May 15. Mol Ther. 2019. PMID: 31129119 Free PMC article.

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