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Heterogeneity but individual constancy of epitopes, isotypes and avidity of factor H autoantibodies in atypical hemolytic uremic syndrome.
Nozal P, Bernabéu-Herrero ME, Uzonyi B, Szilágyi Á, Hyvärinen S, Prohászka Z, Jokiranta TS, Sánchez-Corral P, López-Trascasa M, Józsi M. Nozal P, et al. Among authors: uzonyi b. Mol Immunol. 2016 Feb;70:47-55. doi: 10.1016/j.molimm.2015.12.005. Epub 2015 Dec 15. Mol Immunol. 2016. PMID: 26703217 Free article.
The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease.
Bhattacharjee A, Reuter S, Trojnár E, Kolodziejczyk R, Seeberger H, Hyvärinen S, Uzonyi B, Szilágyi Á, Prohászka Z, Goldman A, Józsi M, Jokiranta TS. Bhattacharjee A, et al. Among authors: uzonyi b. J Biol Chem. 2015 Apr 10;290(15):9500-10. doi: 10.1074/jbc.M114.630871. Epub 2015 Feb 6. J Biol Chem. 2015. PMID: 25659429 Free PMC article.
Factor H-related proteins determine complement-activating surfaces.
Józsi M, Tortajada A, Uzonyi B, Goicoechea de Jorge E, Rodríguez de Córdoba S. Józsi M, et al. Among authors: uzonyi b. Trends Immunol. 2015 Jun;36(6):374-84. doi: 10.1016/j.it.2015.04.008. Epub 2015 May 13. Trends Immunol. 2015. PMID: 25979655 Review.
Selectivity of C3-opsonin targeted complement inhibitors: A distinct advantage in the protection of erythrocytes from paroxysmal nocturnal hemoglobinuria patients.
Schmidt CQ, Harder MJ, Nichols EM, Hebecker M, Anliker M, Höchsmann B, Simmet T, Csincsi ÁI, Uzonyi B, Pappworth IY, Ricklin D, Lambris JD, Schrezenmeier H, Józsi M, Marchbank KJ. Schmidt CQ, et al. Among authors: uzonyi b. Immunobiology. 2016 Apr;221(4):503-11. doi: 10.1016/j.imbio.2015.12.009. Epub 2016 Jan 6. Immunobiology. 2016. PMID: 26792457 Free PMC article.
FHR-1 Binds to C-Reactive Protein and Enhances Rather than Inhibits Complement Activation.
Csincsi ÁI, Szabó Z, Bánlaki Z, Uzonyi B, Cserhalmi M, Kárpáti É, Tortajada A, Caesar JJE, Prohászka Z, Jokiranta TS, Lea SM, Rodríguez de Córdoba S, Józsi M. Csincsi ÁI, et al. Among authors: uzonyi b. J Immunol. 2017 Jul 1;199(1):292-303. doi: 10.4049/jimmunol.1600483. Epub 2017 May 22. J Immunol. 2017. PMID: 28533443 Free article.
The Murine Factor H-Related Protein FHR-B Promotes Complement Activation.
Cserhalmi M, Csincsi ÁI, Mezei Z, Kopp A, Hebecker M, Uzonyi B, Józsi M. Cserhalmi M, et al. Among authors: uzonyi b. Front Immunol. 2017 Sep 19;8:1145. doi: 10.3389/fimmu.2017.01145. eCollection 2017. Front Immunol. 2017. PMID: 28974948 Free PMC article.
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