North P - Search Results

1

MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199.

Benito JM, Godfrey L, Kojima K, Hogdal L, Wunderlich M, Geng H, Marzo I, Harutyunyan KG, Golfman L, North P, Kerry J, Ballabio E, Chonghaile TN, Gonzalo O, Qiu Y, Jeremias I, Debose L, O'Brien E, Ma H, Zhou P, Jacamo R, Park E, Coombes KR, Zhang N, Thomas DA, O'Brien S, Kantarjian HM, Leverson JD, Kornblau SM, Andreeff M, Müschen M, Zweidler-McKay PA, Mulloy JC, Letai A, Milne TA, Konopleva M. Benito JM, et al. Among authors: north p. Cell Rep. 2015 Dec 29;13(12):2715-27. doi: 10.1016/j.celrep.2015.12.003. Epub 2015 Dec 17. Cell Rep. 2015. PMID: 26711339 Free PMC article.

2

RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction.

Wilkinson AC, Ballabio E, Geng H, North P, Tapia M, Kerry J, Biswas D, Roeder RG, Allis CD, Melnick A, de Bruijn MF, Milne TA. Wilkinson AC, et al. Among authors: north p. Cell Rep. 2013 Jan 31;3(1):116-27. doi: 10.1016/j.celrep.2012.12.016. Epub 2013 Jan 24. Cell Rep. 2013. PMID: 23352661 Free PMC article.

3

Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest.

Davies SL, North PS, Dart A, Lakin ND, Hickson ID. Davies SL, et al. Mol Cell Biol. 2004 Feb;24(3):1279-91. doi: 10.1128/MCB.24.3.1279-1291.2004. Mol Cell Biol. 2004. PMID: 14729972 Free PMC article.

4

Role for BLM in replication-fork restart and suppression of origin firing after replicative stress.

Davies SL, North PS, Hickson ID. Davies SL, et al. Nat Struct Mol Biol. 2007 Jul;14(7):677-9. doi: 10.1038/nsmb1267. Epub 2007 Jun 24. Nat Struct Mol Biol. 2007. PMID: 17603497

5

BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges.

Chan KL, North PS, Hickson ID. Chan KL, et al. EMBO J. 2007 Jul 25;26(14):3397-409. doi: 10.1038/sj.emboj.7601777. Epub 2007 Jun 28. EMBO J. 2007. PMID: 17599064 Free PMC article.

6

Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage.

Rao VA, Fan AM, Meng L, Doe CF, North PS, Hickson ID, Pommier Y. Rao VA, et al. Mol Cell Biol. 2005 Oct;25(20):8925-37. doi: 10.1128/MCB.25.20.8925-8937.2005. Mol Cell Biol. 2005. PMID: 16199871 Free PMC article.

7

Increased error-prone non homologous DNA end-joining--a proposed mechanism of chromosomal instability in Bloom's syndrome.

Gaymes TJ, North PS, Brady N, Hickson ID, Mufti GJ, Rassool FV. Gaymes TJ, et al. Oncogene. 2002 Apr 11;21(16):2525-33. doi: 10.1038/sj.onc.1205331. Oncogene. 2002. PMID: 11971187

8

Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome.

Suhasini AN, Rawtani NA, Wu Y, Sommers JA, Sharma S, Mosedale G, North PS, Cantor SB, Hickson ID, Brosh RM Jr. Suhasini AN, et al. EMBO J. 2011 Feb 16;30(4):692-705. doi: 10.1038/emboj.2010.362. Epub 2011 Jan 14. EMBO J. 2011. PMID: 21240188 Free PMC article.

9

Cyclic AMP-dependent protein kinase type I is involved in hypersensitivity of human breast cells to topoisomerase II inhibitors.

Tortora G, Ciardiello F, Damiano V, Pepe S, Bianco C, di Isernia G, Davies SL, North P, Harris AL, Hickson ID, et al. Tortora G, et al. Among authors: north p. Clin Cancer Res. 1995 Jan;1(1):49-56. Clin Cancer Res. 1995. PMID: 9815886

10

Repair and misrepair of site-specific DNA double-strand breaks by human cell extracts.

Ganesh A, North P, Thacker J. Ganesh A, et al. Among authors: north p. Mutat Res. 1993 May;299(3-4):251-9. doi: 10.1016/0165-1218(93)90101-i. Mutat Res. 1993. PMID: 7683092

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