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Page 1
Elevated Plasma Viral Loads in Romidepsin-Treated Simian Immunodeficiency Virus-Infected Rhesus Macaques on Suppressive Combination Antiretroviral Therapy.
Del Prete GQ, Oswald K, Lara A, Shoemaker R, Smedley J, Macallister R, Coalter V, Wiles A, Wiles R, Li Y, Fast R, Kiser R, Lu B, Zheng J, Alvord WG, Trubey CM, Piatak M Jr, Deleage C, Keele BF, Estes JD, Hesselgesser J, Geleziunas R, Lifson JD. Del Prete GQ, et al. Among authors: li y. Antimicrob Agents Chemother. 2015 Dec 28;60(3):1560-72. doi: 10.1128/AAC.02625-15. Antimicrob Agents Chemother. 2015. PMID: 26711758 Free PMC article.
Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound.
Okoye AA, Hansen SG, Vaidya M, Fukazawa Y, Park H, Duell DM, Lum R, Hughes CM, Ventura AB, Ainslie E, Ford JC, Morrow D, Gilbride RM, Legasse AW, Hesselgesser J, Geleziunas R, Li Y, Oswald K, Shoemaker R, Fast R, Bosche WJ, Borate BR, Edlefsen PT, Axthelm MK, Picker LJ, Lifson JD. Okoye AA, et al. Among authors: li y. Nat Med. 2018 Sep;24(9):1430-1440. doi: 10.1038/s41591-018-0130-7. Epub 2018 Aug 6. Nat Med. 2018. PMID: 30082858 Free PMC article.
TLR7 agonist administration to SIV-infected macaques receiving early initiated cART does not induce plasma viremia.
Del Prete GQ, Alvord WG, Li Y, Deleage C, Nag M, Oswald K, Thomas JA, Pyle C, Bosche WJ, Coalter V, Wiles A, Wiles R, Berkemeier B, Hull M, Chipriano E, Silipino L, Fast R, Kiser J, Kiser R, Malys T, Kramer J, Breed MW, Trubey CM, Estes JD, Barnes TL, Hesselgesser J, Geleziunas R, Lifson JD. Del Prete GQ, et al. Among authors: li y. JCI Insight. 2019 Jun 6;4(11):e127717. doi: 10.1172/jci.insight.127717. eCollection 2019 Jun 6. JCI Insight. 2019. PMID: 31167974 Free PMC article.
Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous simian immunodeficiency virus-specific CD8+ T cell clones in rhesus macaques during acute infection.
Minang JT, Trivett MT, Bolton DL, Trubey CM, Estes JD, Li Y, Smedley J, Pung R, Rosati M, Jalah R, Pavlakis GN, Felber BK, Piatak M Jr, Roederer M, Lifson JD, Ott DE, Ohlen C. Minang JT, et al. Among authors: li y. J Immunol. 2010 Jan 1;184(1):315-26. doi: 10.4049/jimmunol.0902410. Epub 2009 Nov 30. J Immunol. 2010. PMID: 19949091 Free PMC article.
Elite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses in Macaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif.
Breed MW, Elser SE, Torben W, Jordan AP, Aye PP, Midkiff C, Schiro F, Sugimoto C, Alvarez-Hernandez X, Blair RV, Somasunderam A, Utay NS, Kuroda MJ, Pahar B, Wiseman RW, O'Connor DH, LaBranche CC, Montefiori DC, Marsh M, Li Y, Piatak M Jr, Lifson JD, Keele BF, Fultz PN, Lackner AA, Hoxie JA. Breed MW, et al. Among authors: li y. J Virol. 2015 Oct;89(20):10156-75. doi: 10.1128/JVI.01134-15. Epub 2015 Jul 29. J Virol. 2015. PMID: 26223646 Free PMC article.
Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection.
Adnan S, Reeves RK, Gillis J, Wong FE, Yu Y, Camp JV, Li Q, Connole M, Li Y, Piatak M Jr, Lifson JD, Li W, Keele BF, Kozlowski PA, Desrosiers RC, Haase AT, Johnson RP. Adnan S, et al. Among authors: li y, li w, li q. PLoS Pathog. 2016 Dec 13;12(12):e1006104. doi: 10.1371/journal.ppat.1006104. eCollection 2016 Dec. PLoS Pathog. 2016. PMID: 27959961 Free PMC article.
Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys.
Barouch DH, Ghneim K, Bosche WJ, Li Y, Berkemeier B, Hull M, Bhattacharyya S, Cameron M, Liu J, Smith K, Borducchi E, Cabral C, Peter L, Brinkman A, Shetty M, Li H, Gittens C, Baker C, Wagner W, Lewis MG, Colantonio A, Kang HJ, Li W, Lifson JD, Piatak M Jr, Sekaly RP. Barouch DH, et al. Among authors: li y, li w, li h. Cell. 2016 Apr 21;165(3):656-67. doi: 10.1016/j.cell.2016.03.021. Epub 2016 Apr 13. Cell. 2016. PMID: 27085913 Free PMC article.
A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection.
Lawrence SP, Elser SE, Torben W, Blair RV, Pahar B, Aye PP, Schiro F, Szeltner D, Doyle-Meyers LA, Haggarty BS, Jordan APO, Romano J, Leslie GJ, Alvarez X, O'Connor DH, Wiseman RW, Fennessey CM, Li Y, Piatak M Jr, Lifson JD, LaBranche CC, Lackner AA, Keele BF, Maness NJ, Marsh M, Hoxie JA. Lawrence SP, et al. Among authors: li y. PLoS Pathog. 2022 Jun 17;18(6):e1010507. doi: 10.1371/journal.ppat.1010507. eCollection 2022 Jun. PLoS Pathog. 2022. PMID: 35714165 Free PMC article.
Trafficking, persistence, and activation state of adoptively transferred allogeneic and autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones during acute and chronic infection of rhesus macaques.
Bolton DL, Minang JT, Trivett MT, Song K, Tuscher JJ, Li Y, Piatak M Jr, O'Connor D, Lifson JD, Roederer M, Ohlen C. Bolton DL, et al. Among authors: li y. J Immunol. 2010 Jan 1;184(1):303-14. doi: 10.4049/jimmunol.0902413. Epub 2009 Nov 30. J Immunol. 2010. PMID: 19949089 Free PMC article.
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