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Page 1
Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons.
Telezhkin V, Schnell C, Yarova P, Yung S, Cope E, Hughes A, Thompson BA, Sanders P, Geater C, Hancock JM, Joy S, Badder L, Connor-Robson N, Comella A, Straccia M, Bombau G, Brown JT, Canals JM, Randall AD, Allen ND, Kemp PJ. Telezhkin V, et al. Among authors: badder l. Am J Physiol Cell Physiol. 2016 Apr 1;310(7):C520-41. doi: 10.1152/ajpcell.00166.2015. Epub 2015 Dec 30. Am J Physiol Cell Physiol. 2016. PMID: 26718628 Free article.
Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA.
Kemp PJ, Rushton DJ, Yarova PL, Schnell C, Geater C, Hancock JM, Wieland A, Hughes A, Badder L, Cope E, Riccardi D, Randall AD, Brown JT, Allen ND, Telezhkin V. Kemp PJ, et al. Among authors: badder l. J Physiol. 2016 Nov 15;594(22):6583-6594. doi: 10.1113/JP270655. J Physiol. 2016. PMID: 27616476 Free PMC article. Review.
Insights into pancreatic β cell energy metabolism using rodent β cell models.
Morten KJ, Potter M, Badder L, Sivathondan P, Dragovic R, Neumann A, Gavin J, Shrestha R, Reilly S, Phadwal K, Lodge TA, Borzychowski A, Cookson S, Mitchell C, Morovat A, Simon AK, Uusimaa J, Hynes J, Poulton J. Morten KJ, et al. Among authors: badder l. Wellcome Open Res. 2019 Sep 25;2:14. doi: 10.12688/wellcomeopenres.10535.3. eCollection 2017. Wellcome Open Res. 2019. PMID: 31754635 Free PMC article.
3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors.
Badder LM, Hollins AJ, Herpers B, Yan K, Ewan KB, Thomas M, Shone JR, Badder DA, Naven M, Ashelford KE, Hargest R, Clarke AR, Esdar C, Buchstaller HP, Treherne JM, Boj S, Ramezanpour B, Wienke D, Price LS, Shaw PH, Dale TC. Badder LM, et al. PLoS One. 2020 Aug 18;15(8):e0235319. doi: 10.1371/journal.pone.0235319. eCollection 2020. PLoS One. 2020. PMID: 32810173 Free PMC article.
A pseudotyped adenovirus serotype 5 vector with serotype 49 fiber knob is an effective vector for vaccine and gene therapy applications.
Bliss CM, Hulin-Curtis SL, Williams M, Marušková M, Davies JA, Statkute E, Baker AT, Stack L, Kerstetter L, Kerr-Jones LE, Milward KF, Russell G, George SJ, Badder LM, Stanton RJ, Coughlan L, Humphreys IR, Parker AL. Bliss CM, et al. Among authors: badder lm. Mol Ther Methods Clin Dev. 2024 Jul 30;32(3):101308. doi: 10.1016/j.omtm.2024.101308. eCollection 2024 Sep 12. Mol Ther Methods Clin Dev. 2024. PMID: 39206304 Free PMC article.
The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.
Krastev DB, Li S, Sun Y, Wicks AJ, Hoslett G, Weekes D, Badder LM, Knight EG, Marlow R, Pardo MC, Yu L, Talele TT, Bartek J, Choudhary JS, Pommier Y, Pettitt SJ, Tutt ANJ, Ramadan K, Lord CJ. Krastev DB, et al. Among authors: badder lm. Nat Cell Biol. 2022 Jan;24(1):62-73. doi: 10.1038/s41556-021-00807-6. Epub 2022 Jan 10. Nat Cell Biol. 2022. PMID: 35013556 Free PMC article.
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.
Zatreanu D, Robinson HMR, Alkhatib O, Boursier M, Finch H, Geo L, Grande D, Grinkevich V, Heald RA, Langdon S, Majithiya J, McWhirter C, Martin NMB, Moore S, Neves J, Rajendra E, Ranzani M, Schaedler T, Stockley M, Wiggins K, Brough R, Sridhar S, Gulati A, Shao N, Badder LM, Novo D, Knight EG, Marlow R, Haider S, Callen E, Hewitt G, Schimmel J, Prevo R, Alli C, Ferdinand A, Bell C, Blencowe P, Bot C, Calder M, Charles M, Curry J, Ekwuru T, Ewings K, Krajewski W, MacDonald E, McCarron H, Pang L, Pedder C, Rigoreau L, Swarbrick M, Wheatley E, Willis S, Wong AC, Nussenzweig A, Tijsterman M, Tutt A, Boulton SJ, Higgins GS, Pettitt SJ, Smith GCM, Lord CJ. Zatreanu D, et al. Among authors: badder lm. Nat Commun. 2021 Jun 17;12(1):3636. doi: 10.1038/s41467-021-23463-8. Nat Commun. 2021. PMID: 34140467 Free PMC article.
13 results