Ellis L - Search Results

1

Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells.

Wu W, Xu C, Ling X, Fan C, Buckley BP, Chernov MV, Ellis L, Li F, Muñoz IG, Wang X. Wu W, et al. Among authors: ellis l. Cell Death Dis. 2015 Dec 31;6(12):e2035. doi: 10.1038/cddis.2015.358. Cell Death Dis. 2015. PMID: 26720344 Free PMC article.

2

Mitochondrial protection impairs BET bromodomain inhibitor-mediated cell death and provides rationale for combination therapeutic strategies.

Lasorsa E, Smonksey M, Kirk JS, Rosario S, Hernandez-Ilizaliturri FJ, Ellis L. Lasorsa E, et al. Among authors: ellis l. Cell Death Dis. 2015 Dec 10;6(12):e2014. doi: 10.1038/cddis.2015.352. Cell Death Dis. 2015. PMID: 26658189 Free PMC article.

3

Inhibition of Hsp90 augments docetaxel therapy in castrate resistant prostate cancer.

Ku S, Lasorsa E, Adelaiye R, Ramakrishnan S, Ellis L, Pili R. Ku S, et al. Among authors: ellis l. PLoS One. 2014 Jul 29;9(7):e103680. doi: 10.1371/journal.pone.0103680. eCollection 2014. PLoS One. 2014. PMID: 25072314 Free PMC article.

4

The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy.

Ellis L, Bots M, Lindemann RK, Bolden JE, Newbold A, Cluse LA, Scott CL, Strasser A, Atadja P, Lowe SW, Johnstone RW. Ellis L, et al. Blood. 2009 Jul 9;114(2):380-93. doi: 10.1182/blood-2008-10-182758. Epub 2009 Apr 21. Blood. 2009. PMID: 19383971 Free PMC article.

5

Combinatorial antitumor effect of HDAC and the PI3K-Akt-mTOR pathway inhibition in a Pten defecient model of prostate cancer.

Ellis L, Ku SY, Ramakrishnan S, Lasorsa E, Azabdaftari G, Godoy A, Pili R. Ellis L, et al. Oncotarget. 2013 Dec;4(12):2225-36. doi: 10.18632/oncotarget.1314. Oncotarget. 2013. PMID: 24163230 Free PMC article.

6

EZH2 inhibition re-sensitizes multidrug resistant B-cell lymphomas to etoposide mediated apoptosis.

Smonskey M, Lasorsa E, Rosario S, Kirk JS, Hernandez-Ilizaliturri FJ, Ellis L. Smonskey M, et al. Among authors: ellis l. Oncoscience. 2016 Jan 29;3(1):21-30. doi: 10.18632/oncoscience.288. eCollection 2016. Oncoscience. 2016. PMID: 26973857 Free PMC article.

7

SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer.

Mu P, Zhang Z, Benelli M, Karthaus WR, Hoover E, Chen CC, Wongvipat J, Ku SY, Gao D, Cao Z, Shah N, Adams EJ, Abida W, Watson PA, Prandi D, Huang CH, de Stanchina E, Lowe SW, Ellis L, Beltran H, Rubin MA, Goodrich DW, Demichelis F, Sawyers CL. Mu P, et al. Among authors: ellis l. Science. 2017 Jan 6;355(6320):84-88. doi: 10.1126/science.aah4307. Science. 2017. PMID: 28059768 Free PMC article.

8

Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma.

Lindemann RK, Newbold A, Whitecross KF, Cluse LA, Frew AJ, Ellis L, Williams S, Wiegmans AP, Dear AE, Scott CL, Pellegrini M, Wei A, Richon VM, Marks PA, Lowe SW, Smyth MJ, Johnstone RW. Lindemann RK, et al. Among authors: ellis l. Proc Natl Acad Sci U S A. 2007 May 8;104(19):8071-6. doi: 10.1073/pnas.0702294104. Epub 2007 Apr 30. Proc Natl Acad Sci U S A. 2007. PMID: 17470784 Free PMC article.

9

Concurrent HDAC and mTORC1 inhibition attenuate androgen receptor and hypoxia signaling associated with alterations in microRNA expression.

Ellis L, Lehet K, Ramakrishnan S, Adelaiye R, Miles KM, Wang D, Liu S, Atadja P, Carducci MA, Pili R. Ellis L, et al. PLoS One. 2011;6(11):e27178. doi: 10.1371/journal.pone.0027178. Epub 2011 Nov 7. PLoS One. 2011. PMID: 22087262 Free PMC article.

10

Class I histone deacetylase inhibitor entinostat suppresses regulatory T cells and enhances immunotherapies in renal and prostate cancer models.

Shen L, Ciesielski M, Ramakrishnan S, Miles KM, Ellis L, Sotomayor P, Shrikant P, Fenstermaker R, Pili R. Shen L, et al. Among authors: ellis l. PLoS One. 2012;7(1):e30815. doi: 10.1371/journal.pone.0030815. Epub 2012 Jan 27. PLoS One. 2012. PMID: 22303460 Free PMC article.

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