Isaacs RJ - Search Results

1

Novel Zn2+ Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents.

Fjellström O, Larsson N, Yasuda S, Tsuchida T, Oguma T, Marley A, Wennberg-Huldt C, Hovdal D, Fukuda H, Yoneyama Y, Sasaki K, Johansson A, Lundqvist S, Brengdahl J, Isaacs RJ, Brown D, Geschwindner S, Benthem L, Priest C, Turnbull A. Fjellström O, et al. Among authors: isaacs rj. PLoS One. 2015 Dec 31;10(12):e0145849. doi: 10.1371/journal.pone.0145849. eCollection 2015. PLoS One. 2015. PMID: 26720709 Free PMC article.

2

Identification of compounds acting as negative allosteric modulators of the LPA₁ receptor.

Ellery J, Dickson L, Cheung T, Ciuclan L, Bunyard P, Mack S, Buffham WJ, Farnaby W, Mitchell P, Brown D, Isaacs R, Barnes M. Ellery J, et al. Eur J Pharmacol. 2018 Aug 15;833:8-15. doi: 10.1016/j.ejphar.2018.05.040. Epub 2018 May 26. Eur J Pharmacol. 2018. PMID: 29807028

3

Characterization of the direct interaction between KcsA-Kv1.3 and its inhibitors.

Xu H, Hill JJ, Michelsen K, Yamane H, Kurzeja RJ, Tam T, Isaacs RJ, Shen F, Tagari P. Xu H, et al. Among authors: isaacs rj. Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):1974-80. doi: 10.1016/j.bbamem.2015.06.011. Epub 2015 Jun 12. Biochim Biophys Acta. 2015. PMID: 26074010 Free article.

4

Physiological regulation of eukaryotic topoisomerase II.

Isaacs RJ, Davies SL, Sandri MI, Redwood C, Wells NJ, Hickson ID. Isaacs RJ, et al. Biochim Biophys Acta. 1998 Oct 1;1400(1-3):121-37. doi: 10.1016/s0167-4781(98)00131-6. Biochim Biophys Acta. 1998. PMID: 9748535 Review.

5

Prolonged low-dose infusion of human parathyroid hormone does not increase femoral cancellous bone volume in ovariectomized rats.

Morley P, Whitfield JF, Willick GE, Ross V, MacLean S, Isaacs RJ, Mendoza E, Barbier JR. Morley P, et al. Among authors: isaacs rj. Eur J Endocrinol. 1999 Jul;141(1):70-4. doi: 10.1530/eje.0.1410070. Eur J Endocrinol. 1999. PMID: 10407226

6

Regulation of the human topoisomerase IIalpha gene promoter in confluence-arrested cells.

Isaacs RJ, Harris AL, Hickson ID. Isaacs RJ, et al. J Biol Chem. 1996 Jul 12;271(28):16741-7. doi: 10.1074/jbc.271.28.16741. J Biol Chem. 1996. PMID: 8663303 Free article.

7

p53 regulates the minimal promoter of the human topoisomerase IIalpha gene.

Sandri MI, Isaacs RJ, Ongkeko WM, Harris AL, Hickson ID, Broggini M, Vikhanskaya F. Sandri MI, et al. Among authors: isaacs rj. Nucleic Acids Res. 1996 Nov 15;24(22):4464-70. doi: 10.1093/nar/24.22.4464. Nucleic Acids Res. 1996. PMID: 8948636 Free PMC article.

8

Topoisomerases II alpha and beta as therapy targets in breast cancer.

Isaacs RJ, Davies SL, Wells NJ, Harris AL. Isaacs RJ, et al. Anticancer Drugs. 1995 Apr;6(2):195-211. doi: 10.1097/00001813-199504000-00002. Anticancer Drugs. 1995. PMID: 7795268 Review.

9

Altered expression and activity of topoisomerases during all-trans retinoic acid-induced differentiation of HL-60 cells.

Aoyama M, Grabowski DR, Isaacs RJ, Krivacic KA, Rybicki LA, Bukowski RM, Ganapathi MK, Hickson ID, Ganapathi R. Aoyama M, et al. Among authors: isaacs rj. Blood. 1998 Oct 15;92(8):2863-70. Blood. 1998. PMID: 9763571 Free article.

10

Down-regulation of human topoisomerase IIalpha expression correlates with relative amounts of specificity factors Sp1 and Sp3 bound at proximal and distal promoter regions.

Williams AO, Isaacs RJ, Stowell KM. Williams AO, et al. Among authors: isaacs rj. BMC Mol Biol. 2007 May 20;8:36. doi: 10.1186/1471-2199-8-36. BMC Mol Biol. 2007. PMID: 17511886 Free PMC article.

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