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Page 1
Rapid and clinically significant response to masitinib in the treatment of mucosal primary esophageal melanoma with somatic KIT exon 11 mutation involving brain metastases: A case report.
Prosvicova J, Lukesova S, Kopecky J, Grim J, Papik Z, Kolarova R, Navratilova B, Dubreuil P, Agopian J, Mansfield C, Moussy A, Hermine O. Prosvicova J, et al. Among authors: dubreuil p. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015 Dec;159(4):695-7. doi: 10.5507/bp.2015.061. Epub 2015 Nov 27. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015. PMID: 26725706 Free article.
Effect of tyrosine kinase inhibitor STI571 on the kinase activity of wild-type and various mutated c-kit receptors found in mast cell neoplasms.
Zermati Y, De Sepulveda P, Féger F, Létard S, Kersual J, Castéran N, Gorochov G, Dy M, Ribadeau Dumas A, Dorgham K, Parizot C, Bieche Y, Vidaud M, Lortholary O, Arock M, Hermine O, Dubreuil P. Zermati Y, et al. Among authors: dubreuil p. Oncogene. 2003 Feb 6;22(5):660-4. doi: 10.1038/sj.onc.1206120. Oncogene. 2003. PMID: 12569358
Rapamycin inhibits growth and survival of D816V-mutated c-kit mast cells.
Gabillot-Carré M, Lepelletier Y, Humbert M, de Sepuvelda P, Hamouda NB, Zappulla JP, Liblau R, Ribadeau-Dumas A, Machavoine F, Letard S, Baude C, Hermant A, Yang Y, Vargaftig J, Bodemer C, Morelon E, Lortholary O, Recher C, Laurent G, Dy M, Arock M, Dubreuil P, Hermine O. Gabillot-Carré M, et al. Among authors: dubreuil p. Blood. 2006 Aug 1;108(3):1065-72. doi: 10.1182/blood-2005-06-2433. Epub 2006 Apr 4. Blood. 2006. PMID: 16597595 Free article.
[Current concepts and treatment advances in systemic mastocytosis].
Georgin-Lavialle S, Barete S, Suarez F, Lepelletier Y, Bodemer C, Dubreuil P, Lortholary O, Hermine O. Georgin-Lavialle S, et al. Among authors: dubreuil p. Rev Med Interne. 2009 Jan;30(1):25-34. doi: 10.1016/j.revmed.2008.01.025. Epub 2008 Apr 10. Rev Med Interne. 2009. PMID: 18406017 Review. French.
Masitinib is safe and effective for the treatment of canine mast cell tumors.
Hahn KA, Ogilvie G, Rusk T, Devauchelle P, Leblanc A, Legendre A, Powers B, Leventhal PS, Kinet JP, Palmerini F, Dubreuil P, Moussy A, Hermine O. Hahn KA, et al. Among authors: dubreuil p. J Vet Intern Med. 2008 Nov-Dec;22(6):1301-9. doi: 10.1111/j.1939-1676.2008.0190.x. Epub 2008 Sep 24. J Vet Intern Med. 2008. PMID: 18823406 Free article. Clinical Trial.
Masitinib in the treatment of active rheumatoid arthritis: results of a multicentre, open-label, dose-ranging, phase 2a study.
Tebib J, Mariette X, Bourgeois P, Flipo RM, Gaudin P, Le Loët X, Gineste P, Guy L, Mansfield CD, Moussy A, Dubreuil P, Hermine O, Sibilia J. Tebib J, et al. Among authors: dubreuil p. Arthritis Res Ther. 2009;11(3):R95. doi: 10.1186/ar2740. Epub 2009 Jun 23. Arthritis Res Ther. 2009. PMID: 19549290 Free PMC article. Clinical Trial.
Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT.
Dubreuil P, Letard S, Ciufolini M, Gros L, Humbert M, Castéran N, Borge L, Hajem B, Lermet A, Sippl W, Voisset E, Arock M, Auclair C, Leventhal PS, Mansfield CD, Moussy A, Hermine O. Dubreuil P, et al. PLoS One. 2009 Sep 30;4(9):e7258. doi: 10.1371/journal.pone.0007258. PLoS One. 2009. PMID: 19789626 Free PMC article.
Pediatric mastocytosis is a clonal disease associated with D816V and other activating c-KIT mutations.
Bodemer C, Hermine O, Palmérini F, Yang Y, Grandpeix-Guyodo C, Leventhal PS, Hadj-Rabia S, Nasca L, Georgin-Lavialle S, Cohen-Akenine A, Launay JM, Barete S, Feger F, Arock M, Catteau B, Sans B, Stalder JF, Skowron F, Thomas L, Lorette G, Plantin P, Bordigoni P, Lortholary O, de Prost Y, Moussy A, Sobol H, Dubreuil P. Bodemer C, et al. Among authors: dubreuil p. J Invest Dermatol. 2010 Mar;130(3):804-15. doi: 10.1038/jid.2009.281. Epub 2009 Oct 29. J Invest Dermatol. 2010. PMID: 19865100 Free article.
340 results